5J9O

tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 1-(2-(methylamino)-1H-benzo[d]imidazol-6-yl)guanidine

Summary for 5J9O

• Entry DOI: 10.2210/pdb5j9o/pdb
• Related: 1P0D 3S1G 4KWO 4PUK 5I07 5J9M 5J9N
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (6 entities in total)
• Functional Keywords: benzimidazole-derivatives, shigellosis, transferase, transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• Total number of polymer chains: 1
• Total formula weight: 43414.99

Authors

Ehrmann, F.R.,Heine, A.,Klebe, G. (deposition date: 2016-04-10, release date: 2017-05-24, Last modification date: 2024-01-10)

• Primary citation: Ehrmann, F.R.,Hohn, C.,Heine, A.,Diederich, F.,Klebe, G.; Benzimidazole-based Inhibitors as a Novel Scaffold to Inhibit Z.mobilis TGT and Study Protein Flexibility and the Contributions of Active Site Residues to Binding Affinity of lin-Benzopurines.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.41 Å)