8R1F
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![BU of 8r1f by Molmil](/molmil-images/mine/8r1f) | Monomeric E6AP-E6-p53 ternary complex | 分子名称: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | 著者 | Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H. | 登録日 | 2023-11-01 | 公開日 | 2023-12-06 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Structural insights into viral hijacking of p53 by E6 and E6AP Biorxiv, 2023
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8R1G
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![BU of 8r1g by Molmil](/molmil-images/mine/8r1g) | Dimeric ternary structure of E6AP-E6-p53 | 分子名称: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | 著者 | Sandate, C.R, Chakrabory, D, Kater, L, Kempf, G, Thoma, N.H. | 登録日 | 2023-11-01 | 公開日 | 2023-12-06 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | 主引用文献 | Structural insights into viral hijacking of p53 by E6 and E6AP Biorxiv, 2023
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4V8N
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![BU of 4v8n by Molmil](/molmil-images/mine/4v8n) | The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site. | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Voorhees, R.M, Mandal, D, Neubauer, C, Koehrer, C, RajBhandary, U.L, Ramakrishnan, V. | 登録日 | 2013-02-13 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome Nat.Struct.Mol.Biol., 20, 2013
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4V5G
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![BU of 4v5g by Molmil](/molmil-images/mine/4v5g) | The crystal structure of the 70S ribosome bound to EF-Tu and tRNA | 分子名称: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. | 登録日 | 2009-09-01 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA. Science, 326, 2009
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5EC9
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![BU of 5ec9 by Molmil](/molmil-images/mine/5ec9) | Retinoic acid receptor alpha in complex with chiral dihydrobenzofuran benzoic acid 9a and a fragment of the coactivator TIF2 | 分子名称: | 4-[(11S,15R)-4,4,7,7-Tetramethyl-16-oxatetracyclo[8.6.0.03,8.011,15]hexadeca-1(10),2,8-trien-11-yl]benzoic acid, LYS-HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP, Retinoic acid receptor RXR-alpha | 著者 | Leysen, S, Ottmann, C, Schafer, A, Scheepstra, M, Brunsveld, L, Sunden, R, Ma, J.N, Burnstein, E.S, Olsson, R. | 登録日 | 2015-10-20 | 公開日 | 2016-03-09 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer Activation. J.Med.Chem., 59, 2016
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5VQL
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![BU of 5vql by Molmil](/molmil-images/mine/5vql) | |
2W1T
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![BU of 2w1t by Molmil](/molmil-images/mine/2w1t) | Crystal Structure of B. subtilis SpoVT | 分子名称: | STAGE V SPORULATION PROTEIN T | 著者 | Asen, I, Djuranovic, S, Lupas, A.N, Zeth, K. | 登録日 | 2008-10-20 | 公開日 | 2008-11-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Spovt, the Final Modulator of Gene Expression During Spore Development in Bacillus Subtilis J.Mol.Biol., 386, 2009
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4MBE
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![BU of 4mbe by Molmil](/molmil-images/mine/4mbe) | Sac3:Sus1:Cdc31:Nup1 complex | 分子名称: | CALCIUM ION, Cell division control protein 31, Nuclear mRNA export protein SAC3, ... | 著者 | Jani, D, Meineke, B, Stewart, M. | 登録日 | 2013-08-19 | 公開日 | 2014-07-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.612 Å) | 主引用文献 | Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export. Nucleic Acids Res., 42, 2014
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5VXZ
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![BU of 5vxz by Molmil](/molmil-images/mine/5vxz) | High-affinity AXL decoy receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Mathrews, I.I, Kapur, S, Kariolis, M.S, Cochran, J.R. | 登録日 | 2017-05-24 | 公開日 | 2017-06-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J. Clin. Invest., 127, 2017
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4M8H
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![BU of 4m8h by Molmil](/molmil-images/mine/4m8h) | CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (R)4-METHYL 9cUAB30 AND COACTIVATOR PEPTIDE GRIP-1 | 分子名称: | (2E,6Z,8E)-3,7-dimethyl-8-[(4R)-4-methyl-3,4-dihydronaphthalen-1(2H)-ylidene]octa-2,6-dienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | 著者 | Xia, G, Smith, C.D, Muccio, D.D. | 登録日 | 2013-08-13 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention. Bioorg.Med.Chem., 22, 2014
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5W4R
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![BU of 5w4r by Molmil](/molmil-images/mine/5w4r) | Structure of RORgt bound to a tertiary alcohol | 分子名称: | 1-{4-[(R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]piperidin-1-yl}ethan-1-one, Nuclear receptor ROR-gamma | 著者 | Spurlino, J. | 登録日 | 2017-06-12 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | 主引用文献 | 6-Substituted quinolines as ROR gamma t inverse agonists. Bioorg. Med. Chem. Lett., 27, 2017
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4LQ9
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![BU of 4lq9 by Molmil](/molmil-images/mine/4lq9) | Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2 | 分子名称: | MAGNESIUM ION, RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid | 著者 | Milani, M, Tarantino, D, Mastrangelo, E, Croci, R. | 登録日 | 2013-07-17 | 公開日 | 2014-02-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase. Antiviral Res., 102, 2014
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5EGS
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![BU of 5egs by Molmil](/molmil-images/mine/5egs) | Human PRMT6 with bound fragment-type inhibitor | 分子名称: | 2-[4-(phenylmethyl)piperidin-1-yl]ethanamine, Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Steuber, H, Egner, U, Kania, J, Wu, H, Brown, P.J. | 登録日 | 2015-10-27 | 公開日 | 2016-02-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor. J.Med.Chem., 59, 2016
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8I9V
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![BU of 8i9v by Molmil](/molmil-images/mine/8i9v) | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-2 | 分子名称: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | 著者 | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | 登録日 | 2023-02-07 | 公開日 | 2023-05-17 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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5W4V
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![BU of 5w4v by Molmil](/molmil-images/mine/5w4v) | Structure of RORgt bound to a tertiary alcohol | 分子名称: | (R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)[6-(trifluoromethyl)pyridin-3-yl]methanol, Nuclear receptor ROR-gamma | 著者 | Spurlino, J, Hars, U. | 登録日 | 2017-06-13 | 公開日 | 2017-12-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | 6-Substituted quinolines as ROR gamma t inverse agonists. Bioorg. Med. Chem. Lett., 27, 2017
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7OJ0
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![BU of 7oj0 by Molmil](/molmil-images/mine/7oj0) | Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | 登録日 | 2021-05-13 | 公開日 | 2021-09-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide. Nucleic Acids Res., 49, 2021
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7OIZ
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![BU of 7oiz by Molmil](/molmil-images/mine/7oiz) | Cryo-EM structure of 70S ribosome stalled with TnaC peptide | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | 登録日 | 2021-05-13 | 公開日 | 2021-09-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide. Nucleic Acids Res., 49, 2021
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5EJV
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![BU of 5ejv by Molmil](/molmil-images/mine/5ejv) | RORy in complex with T090131718 and Coactivator peptide EBI96 | 分子名称: | EBI96 Coactivator Peptide, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, Nuclear receptor ROR-gamma | 著者 | Marcotte, D.M. | 登録日 | 2015-11-02 | 公開日 | 2016-04-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Discovery of biaryls as ROR gamma inverse agonists by using structure-based design. Bioorg.Med.Chem.Lett., 26, 2016
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4ME7
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![BU of 4me7 by Molmil](/molmil-images/mine/4me7) | |
2VV4
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![BU of 2vv4 by Molmil](/molmil-images/mine/2vv4) | hPPARgamma Ligand binding domain in complex with 6-oxoOTE | 分子名称: | (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid, (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | 著者 | Itoh, T, Fairall, L, Schwabe, J.W.R. | 登録日 | 2008-06-02 | 公開日 | 2008-08-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008
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5YC9
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![BU of 5yc9 by Molmil](/molmil-images/mine/5yc9) | |
4W5Q
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![BU of 4w5q by Molmil](/molmil-images/mine/4w5q) | |
4W4U
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![BU of 4w4u by Molmil](/molmil-images/mine/4w4u) | |
4W5R
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![BU of 4w5r by Molmil](/molmil-images/mine/4w5r) | |
5LGF
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![BU of 5lgf by Molmil](/molmil-images/mine/5lgf) | |