4ME7

Crystal structure of Bacillus subtilis toxin MazF in complex with cognate antitoxin MazE

Summary for 4ME7

Entry DOI	10.2210/pdb4me7/pdb
Related	4MDX
Descriptor	mRNA interferase EndoA, Antitoxin EndoAI (3 entities in total)
Functional Keywords	toxin-antitoxin system, maze-mazf, stress response, mrna clevage, maze, antitoxin, mazf, mrna interferase, endoa, ydce, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bacillus subtilis subsp. subtilis More
Total number of polymer chains	6
Total formula weight	74401.32
Authors	Simanshu, D.K.,Patel, D.J. (deposition date: 2013-08-25, release date: 2013-10-23, Last modification date: 2023-12-06)
Primary citation	Simanshu, D.K.,Yamaguchi, Y.,Park, J.H.,Inouye, M.,Patel, D.J. Structural Basis of mRNA Recognition and Cleavage by Toxin MazF and Its Regulation by Antitoxin MazE in Bacillus subtilis. Mol.Cell, 52:447-458, 2013 Cited by PubMed: 24120662 DOI: 10.1016/j.molcel.2013.09.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.918 Å)

Structure validation