PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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1FX4	STRUCTURE ANALYSIS OF ADENYLATE CYCLASES FROM TRYPANOSOMA BRUCEI IN THEIR MONOMERIC STATE 分子名称: MAGNESIUM ION, RECEPTOR-TYPE ADENYLATE CYCLASE GRESAG 4.3 著者 Bieger, B, Essen, L.O. 登録日 2000-09-25 公開日 2001-02-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state. EMBO J., 20, 2001
8A5X	Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with MM1373 分子名称: 4-azanyl-7-[3-(hydroxymethyl)phenyl]quinazoline-6-carboxamide, Phosphatidylinositol 4-kinase type 2-beta,Endolysin 著者 Klima, M, Boura, E. 登録日 2022-06-16 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorg.Med.Chem.Lett., 76, 2022
7QRD	Crystal structure of mouse CARM1 in complex with histone H3_10-25 分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, 1,2-ETHANEDIOL, Histone-arginine methyltransferase CARM1, ... 著者 Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J. 登録日 2022-01-11 公開日 2022-12-28 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 CARM1 Transition State Mimics To Be Published
8AE5	Crystal structure of human legumain in complex with macrocypin 1a 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Legumain, ... 著者 Elamin, T, Brandstetter, H, Dall, E. 登録日 2022-07-12 公開日 2022-09-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural and functional studies of legumain-mycocypin complexes revealed a competitive, exosite-regulated mode of interaction. J.Biol.Chem., 298, 2022
2DW5	Crystal structure of human peptidylarginine deiminase 4 in complex with N-alpha-benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine amide 分子名称: CALCIUM ION, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, Protein-arginine deiminase type-4, ... 著者 Luo, Y, Arita, K, Sato, M, Thompson, P.R. 登録日 2006-08-04 公開日 2006-10-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization Biochemistry, 45, 2006
3S9O	The Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase showing N-terminal interactions in cis 分子名称: CHLORIDE ION, Focal adhesion kinase 1, SODIUM ION 著者 Arold, S.T. 登録日 2011-06-01 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells. J.Biol.Chem., 290, 2015
6L47	Structure of the human sterol O-acyltransferase 1 in complex with CI-976 分子名称: 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CHOLESTEROL, Sterol O-acyltransferase 1 著者 Chen, L, Guan, C, Niu, Y. 登録日 2019-10-16 公開日 2020-04-29 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nat Commun, 11, 2020
6A60	Crystal structure of human FXR/RXR-LBD heterodimer bound to GW4064 and 9cRA and SRC1 分子名称: (9cis)-retinoic acid, 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid, Bile acid receptor, ... 著者 Wang, N, Liu, J. 登録日 2018-06-25 公開日 2018-10-10 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
2DEX	Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal peptide including Arg17 分子名称: 10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ... 著者 Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. 登録日 2006-02-18 公開日 2006-04-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006
4MRA	Crystal structure of Gpb in complex with QUERCETIN 分子名称: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ... 著者 Kantsadi, L.A, Chatzileontiadou, S.M.D, Leonidas, D.D. 登録日 2013-09-17 公開日 2014-05-07 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase. Food Chem.Toxicol., 67, 2014
1ZCP	Crystal Structure of a catalytic site mutant E. coli TrxA (CACA) 分子名称: Thioredoxin 1 著者 Collet, J.-F, Peisach, D, Bardwell, J.C, Xu, Z. 登録日 2005-04-12 公開日 2005-08-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The crystal structure of TrxA(CACA): Insights into the formation of a [2Fe-2S] iron-sulfur cluster in an Escherichia coli thioredoxin mutant Protein Sci., 14, 2005
1ZD2	Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-ethanoic acid complex 分子名称: MAGNESIUM ION, N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE, PHOSPHATE ION, ... 著者 Gomez, G.A, Morisseau, C, Hammock, B.D, Christianson, D.W. 登録日 2005-04-14 公開日 2006-03-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Human soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids Protein Sci., 15, 2006
1FR3	THE HIGH RESOLUTION STRUCTURE OF A MOLYBDATE BINDING PROTEIN FROM SPOROMUSA OVATA 分子名称: MOLYBDATE/TUNGSTATE BINDING PROTEIN, TUNGSTATE(VI)ION 著者 Wagner, U.G, Stupperich, E, Kratky, C. 登録日 2000-09-07 公開日 2000-12-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the molybdate/tungstate binding protein mop from Sporomusa ovata. Structure Fold.Des., 8, 2000
3NVQ	Molecular mechanism of guidance cue recognition 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-C1, ... 著者 Juo, Z, Liu, H, Shim, A, Focia, P, Chen, X, Garcia, C, He, X. 登録日 2010-07-08 公開日 2010-09-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1. Cell(Cambridge,Mass.), 142, 2010
3FIS	THE MOLECULAR STRUCTURE OF WILD-TYPE AND A MUTANT FIS PROTEIN: RELATIONSHIP BETWEEN MUTATIONAL CHANGES AND RECOMBINATIONAL ENHANCER FUNCTION OR DNA BINDING 分子名称: FACTOR FOR INVERSION STIMULATION (FIS) 著者 Yuan, H.S, Finkel, S.E, Feng, J-A, Johnson, R.C, Dickerson, R.E. 登録日 1991-08-12 公開日 1993-10-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The molecular structure of wild-type and a mutant Fis protein: relationship between mutational changes and recombinational enhancer function or DNA binding. Proc.Natl.Acad.Sci.USA, 88, 1991
4I5N	Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation 分子名称: CALCIUM ION, MANGANESE (II) ION, Microcystin-LR (MCLR) bound form, ... 著者 Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y. 登録日 2012-11-28 公開日 2013-05-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Res., 23, 2013
5BKC	Crystal structure of AAD-1 in complex with (R)-diclofop, Mn(II), and 2-oxoglutarate 分子名称: (2R)-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}propanoic acid, (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, ... 著者 Chekan, J.R, Nair, S.K. 登録日 2019-06-02 公開日 2019-06-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
8A4T	crystal structures of diastereomer (S,S,S)-13b (13b-K) in complex with the SARS-CoV-2 Mpro 分子名称: 3C-like proteinase nsp5, CHLORIDE ION, ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate 著者 Ibrahim, M, Hilgenfeld, R, Zhang, L. 登録日 2022-06-13 公開日 2022-10-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Diastereomeric Resolution Yields Highly Potent Inhibitor of SARS-CoV-2 Main Protease. J.Med.Chem., 65, 2022
1FSN	X-RAY CRYSTAL STRUCTURE OF METAL-FREE F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT 分子名称: CARBONIC ANHYDRASE II 著者 Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W. 登録日 2000-09-11 公開日 2001-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II. Biochemistry, 39, 2000
3EVV	Crystal Structure of Calcium bound dimeric GCAMP2 (#2) 分子名称: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... 著者 Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. 登録日 2008-10-13 公開日 2008-12-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for Calcium Sensing by GCaMP2. Structure, 16, 2008
7MOQ	The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ... 著者 Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H. 登録日 2021-05-03 公開日 2021-07-14 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM. Embo Rep., 22, 2021
3W0E	Structure of elastase inhibitor AFUEI (crystal form II) 分子名称: Elastase inhibitor AFUEI 著者 Imada, K, Sakuma, M, Okumura, Y, Ogawa, K, Nikai, T, Homma, M. 登録日 2012-10-29 公開日 2013-05-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray Structure Analysis and Characterization of AFUEI, an Elastase Inhibitor from Aspergillus fumigatus J.Biol.Chem., 288, 2013
1ZH9	carbonic anhydrase II in complex with N-4-Methyl-1-piperazinyl-N'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE, Carbonic anhydrase II, ... 著者 Honndorf, V.S, Heine, A, Klebe, G, Supuran, C.T. 登録日 2005-04-23 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 carbonic anhydrase II in complex with N-4-Methyl-1-piperazinyl-N'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor To be Published
3OIM	Human Carbonic anhydrase II bound by 2-Ethylestradiol 3-O-sulfamate 分子名称: (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. 登録日 2010-08-19 公開日 2011-07-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011
8AA5	Cryo-EM structure of the strand transfer complex of the TnsB transposase (type V-K CRISPR-associated transposon) 分子名称: LE_PolyA, LE_Target, RE_PolyA, ... 著者 Tenjo-Castano, F, Sofos, N, Lopez-Mendez, B, Stutzke, L.S, Fuglsang, A, Stella, S, Montoya, G. 登録日 2022-06-30 公開日 2022-10-19 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.46 Å) 主引用文献 Structure of the TnsB transposase-DNA complex of type V-K CRISPR-associated transposon. Nat Commun, 13, 2022

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