3S9O
The Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase showing N-terminal interactions in cis
Summary for 3S9O
| Entry DOI | 10.2210/pdb3s9o/pdb |
| Related | 1K04 1K05 |
| Descriptor | Focal adhesion kinase 1, SODIUM ION, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | 4-helix bundle, focal adhesion targeting, protein binding, phosphorylation, nucleus, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell junction, focal adhesion: Q05397 |
| Total number of polymer chains | 3 |
| Total formula weight | 54393.02 |
| Authors | Arold, S.T. (deposition date: 2011-06-01, release date: 2012-06-06, Last modification date: 2023-09-13) |
| Primary citation | Kadare, G.,Gervasi, N.,Brami-Cherrier, K.,Blockus, H.,El Messari, S.,Arold, S.T.,Girault, J.A. Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells. J.Biol.Chem., 290:478-491, 2015 Cited by PubMed: 25391654DOI: 10.1074/jbc.M114.593632 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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