3S9O
The Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase showing N-terminal interactions in cis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005925 | cellular_component | focal adhesion |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007172 | biological_process | signal complex assembly |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005925 | cellular_component | focal adhesion |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0007172 | biological_process | signal complex assembly |
| C | 0004713 | molecular_function | protein tyrosine kinase activity |
| C | 0005925 | cellular_component | focal adhesion |
| C | 0006468 | biological_process | protein phosphorylation |
| C | 0007172 | biological_process | signal complex assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 34 |
| Chain | Residue |
| A | PRO976 |
| A | ALA977 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 36 |
| Chain | Residue |
| A | LYS923 |
| A | ARG1042 |
| B | HOH27 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA C 35 |
| Chain | Residue |
| C | ALA977 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER910 | |
| B | SER910 | |
| C | SER910 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| A | THR914 | |
| B | THR914 | |
| C | THR914 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:12387730, ECO:0000269|PubMed:19339212 |
| Chain | Residue | Details |
| A | TYR925 | |
| B | TYR925 | |
| C | TYR925 |
