1ZH9

carbonic anhydrase II in complex with N-4-Methyl-1-piperazinyl-N'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor

Summary for 1ZH9

• Entry DOI: 10.2210/pdb1zh9/pdb
• Related: 1OQ5 1Z9Y 1ZFQ
• Descriptor: Carbonic anhydrase II, ZINC ION, 4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE, ... (5 entities in total)
• Functional Keywords: 10 stranded, twisted beta-sheets, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 29909.87

Authors

Honndorf, V.S.,Heine, A.,Klebe, G.,Supuran, C.T. (deposition date: 2005-04-23, release date: 2006-05-23, Last modification date: 2024-03-13)

• Primary citation: Honndorf, V.S.,Heine, A.,Klebe, G.,Supuran, C.T.; carbonic anhydrase II in complex with N-4-Methyl-1-piperazinyl-N'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)