2DW5

Crystal structure of human peptidylarginine deiminase 4 in complex with N-alpha-benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine amide

Summary for 2DW5

Entry DOI	10.2210/pdb2dw5/pdb
Related	1WD8 1WD9 1WDA 2DEW 2DEX 2DEY
Descriptor	Protein-arginine deiminase type-4, CALCIUM ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	protein-inhibitor complex, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9UM07
Total number of polymer chains	1
Total formula weight	75730.81
Authors	Luo, Y.,Arita, K.,Sato, M.,Thompson, P.R. (deposition date: 2006-08-04, release date: 2006-10-17, Last modification date: 2023-10-25)
Primary citation	Luo, Y.,Arita, K.,Bhatia, M.,Knuckley, B.,Lee, Y.H.,Stallcup, M.R.,Sato, M.,Thompson, P.R. Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization Biochemistry, 45:11727-11736, 2006 Cited by PubMed: 17002273 DOI: 10.1021/bi061180d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation