6L47
Structure of the human sterol O-acyltransferase 1 in complex with CI-976
Summary for 6L47
Entry DOI | 10.2210/pdb6l47/pdb |
EMDB information | 0831 |
Descriptor | Sterol O-acyltransferase 1, 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CHOLESTEROL (3 entities in total) |
Functional Keywords | soat, acat, mboat, membrane protein, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 116149.98 |
Authors | |
Primary citation | Guan, C.,Niu, Y.,Chen, S.C.,Kang, Y.,Wu, J.X.,Nishi, K.,Chang, C.C.Y.,Chang, T.Y.,Luo, T.,Chen, L. Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nat Commun, 11:2478-2478, 2020 Cited by PubMed: 32424158DOI: 10.1038/s41467-020-16288-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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