PDB: 12119 件ウェブページステータス検索Chemie searchBIRD

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8TFQ	Fab from C10-S66K antibody in complex with fentanyl 分子名称: Heavy chain from Fab of C10_S66K antibody, Light chain from Fab of C10_S66K antibody, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide 著者 Pholcharee, T, Wilson, I.A. 登録日 2023-07-11 公開日 2023-08-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. Acs Chem Neurosci, 14, 2023
1JAZ	Crystal Structure of Monoclinic Form of D90E Mutant of Escherichia coli Asparaginase II 分子名称: L-ASPARAGINASE II, ZINC ION 著者 Borek, D, Kozak, M, Jaskolski, M. 登録日 2001-06-01 公開日 2003-09-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structure of active site mutant of antileukemic L-asparaginase reveals conserved zinc-binding site. Febs J., 281, 2014
1JJA	CRYSTAL STRUCTURE OF ORTHORHOMBIC FORM OF D90E MUTANT OF ESCHERICHIA COLI L-ASPARAGINASE II 分子名称: L-ASPARAGINASE II 著者 Borek, D, Kozak, M, Jaskolski, M. 登録日 2001-07-04 公開日 2003-09-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of active site mutant of antileukemic L-asparaginase reveals conserved zinc-binding site. Febs J., 281, 2014
4UDF	STRUCTURAL BASIS OF HUMAN PARECHOVIRUS NEUTRALIZATION BY HUMAN MONOCLONAL ANTIBODIES 分子名称: HUMAN MONOCLONAL ANTIBODY, Protein VP0, Protein VP3 著者 Shakeel, S, Westerhuis, B.M, Ora, A, Koen, G, Bakker, A.Q, Claassen, Y, Beaumont, T, Wolthers, K.C, Butcher, S.J. 登録日 2014-12-10 公開日 2015-07-22 最終更新日 2018-10-03 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Structural Basis of Human Parechovirus Neutralization by Human Monoclonal Antibodies. J. Virol., 89, 2015
5L8Q	Structure of deformed wing virus, a honeybee pathogen 分子名称: URIDINE-5'-MONOPHOSPHATE, VP1, VP2, ... 著者 Skubnik, K, Novacek, J, Fuzik, T, Pridal, A, Paxton, R, Plevka, P. 登録日 2016-06-08 公開日 2017-03-29 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of deformed wing virus, a major honey bee pathogen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5L7Q	Structure of deformed wing virus, a honeybee pathogen 分子名称: VP1, vp2, vp3 著者 Skubnik, K, Novacek, J, Fuzik, T, Pridal, A, Paxton, R, Plevka, P. 登録日 2016-06-03 公開日 2017-03-29 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of deformed wing virus, a major honey bee pathogen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5C90	Staphylococcus aureus ClpP mutant - Y63A 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit 著者 Ye, F, Liu, H, Zhang, J, Gan, J, Yang, C.-G. 登録日 2015-06-26 公開日 2016-05-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Characterization of Gain-of-Function Mutant Provides New Insights into ClpP Structure Acs Chem.Biol., 11, 2016
4ZXT	Complex of ERK2 with catechol 分子名称: AMMONIUM ION, CATECHOL, Mitogen-activated protein kinase 1, ... 著者 Kurinov, I, Malakhova, M. 登録日 2015-05-20 公開日 2016-05-25 最終更新日 2016-10-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A natural small molecule, catechol, induces c-Myc degradation by directly targeting ERK2 in lung cancer. Oncotarget, 7, 2016
1QZY	Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt 分子名称: (E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE, COBALT (II) ION, Methionine aminopeptidase 2, ... 著者 Eck, M.J, Song, H.K, Morollo, A. 登録日 2003-09-18 公開日 2003-11-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors. J.Biol.Chem., 278, 2003
8YKI	FGFR-1 in complex with ligand tasurgratinib 分子名称: CHLORIDE ION, Fibroblast growth factor receptor 1, Tasurgratinib 著者 Ikemori-Kawada, M, Watanabe Miyano, S. 登録日 2024-03-05 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Antitumor Activity of Tasurgratinib as an Orally Available FGFR1-3 Inhibitor in Cholangiocarcinoma Models With FGFR2-fusion. Anticancer Res., 44, 2024
8YRG	CryoEM structure of fospropofol-bound MRGPRX4-Gq complex 分子名称: Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Cao, C, Fay, J.F, Roth, B.L. 登録日 2024-03-21 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Sci Transl Med, 16, 2024
4K68	Structure of a novel GH10 endoxylanase retrieved from sugarcane soil metagenome 分子名称: GH10 xylanase, GLYCEROL 著者 Santos, C.R, Polo, C.C, Alvarez, T.M, Paixao, D.A.A, Almeida, R.F, Pereira, I.O, Squina, F.M, Murakami, M.T. 登録日 2013-04-15 公開日 2013-10-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Development and biotechnological application of a novel endoxylanase family GH10 identified from sugarcane soil metagenome. Plos One, 8, 2013
6U4O	Crystal structure of recombinant class II fumarase from Schistosoma mansoni 分子名称: (2S)-2-hydroxybutanedioic acid, ACETATE ION, Fumarate hydratase, ... 著者 Cardoso, I.A, Nonato, M.C. 登録日 2019-08-26 公開日 2020-09-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Characterization of class II fumarase from Schistosoma mansoni provides the molecular basis for selective inhibition. Int.J.Biol.Macromol., 175, 2021
8H2D	The hypothetical protein from Mycobacterium tuberculosis mutant - E47A 分子名称: Uncharacterized protein Rv1546 著者 Kim, D.H, Na, Y, Lee, B.J. 登録日 2022-10-05 公開日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Domain swapping of the C-terminal helix promotes the dimerization of a novel ribonuclease protein from Mycobacterium tuberculosis. Protein Sci., 32, 2023
8H0H	Hypotethical protein from Mycobacterium tuberculsosis 分子名称: Uncharacterized protein Rv1546 著者 Kim, D.H, Na, Y, Lee, B.J. 登録日 2022-09-29 公開日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Domain swapping of the C-terminal helix promotes the dimerization of a novel ribonuclease protein from Mycobacterium tuberculosis. Protein Sci., 32, 2023
5FCW	HDAC8 Complexed with a Hydroxamic Acid 分子名称: 4-naphthalen-1-yl-~{N}-oxidanyl-benzamide, GLYCEROL, HEXAETHYLENE GLYCOL, ... 著者 Cole, K.E, Perry, K. 登録日 2015-12-15 公開日 2016-10-26 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.979 Å) 主引用文献 Structure of 'linkerless' hydroxamic acid inhibitor-HDAC8 complex confirms the formation of an isoform-specific subpocket. J.Struct.Biol., 195, 2016
8UKY	Crystal structure of BAK in complex with inhibiting antibody 14G6 分子名称: 1,2-ETHANEDIOL, 14G6 Fab heavy chain, 14G6 Fab light chain, ... 著者 Miller, M.S, Czabotar, P.E. 登録日 2023-10-15 公開日 2024-04-10 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.398 Å) 主引用文献 A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells. Cell Death Differ., 31, 2024
6V78	OmpK37 porin 分子名称: OmpK37 著者 Rocker, A, Lithgow, T. 登録日 2019-12-08 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Global Trends in Proteome Remodeling of the Outer Membrane Modulate Antimicrobial Permeability in Klebsiella pneumoniae. Mbio, 11, 2020
5HF9	Crystal structure of human acetylcholinesterase in complex with paraoxon and HI6 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. 登録日 2016-01-06 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016
2UZH	Mycobacterium smegmatis 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF) 分子名称: 1,2-ETHANEDIOL, 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ... 著者 Buetow, L, Brown, A.C, Parish, T, Hunter, W.N. 登録日 2007-04-27 公開日 2007-11-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Structure of Mycobacteria 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase, an Essential Enzyme, Provides a Platform for Drug Discovery. Bmc Struct.Biol., 7, 2007
5HF8	Crystal structure of human acetylcholinesterase in complex with paraoxon (alternative acyl loop conformation) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. 登録日 2016-01-06 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016
5I3U	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE N-SITE COMPLEX; CATALYTIC INCORPORATION OF AZTMP to A DNA aptamer in CRYSTAL 分子名称: DNA (39-MER), GLYCEROL, HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, ... 著者 Das, K, Arnold, E. 登録日 2016-02-11 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11, 2016
5HF5	Crystal structure of human acetylcholinesterase in complex with paraoxon in the unaged state (predominant acyl loop conformation) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. 登録日 2016-01-06 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.152 Å) 主引用文献 Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016
5HF6	Crystal structure of human acetylcholinesterase in complex with paraoxon in the aged state 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. 登録日 2016-01-06 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016
5HFA	Crystal structure of human acetylcholinesterase in complex with paraoxon and 2-PAM 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. 登録日 2016-01-06 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016

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