1QZY

Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt

Summary for 1QZY

Entry DOI	10.2210/pdb1qzy/pdb
Descriptor	Methionine aminopeptidase 2, COBALT (II) ION, (E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE, ... (5 entities in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	53566.00
Authors	Eck, M.J.,Song, H.K.,Morollo, A. (deposition date: 2003-09-18, release date: 2003-11-25, Last modification date: 2011-07-13)
Primary citation	Towbin, H.,Bair, K.W.,DeCaprio, J.A.,Eck, M.J.,Kim, S.,Kinder, F.R.,Morollo, A.,Mueller, D.R.,Schindler, P.,Song, H.K.,van Oostrum, J.,Versace, R.W.,Voshol, H.,Wood, J.,Zabludoff, S.,Phillips, P.E. Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors. J.Biol.Chem., 278:52964-52971, 2003 Cited by PubMed: 14534293 DOI: 10.1074/jbc.M309039200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation