1QZY
Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt
Summary for 1QZY
Entry DOI | 10.2210/pdb1qzy/pdb |
Descriptor | Methionine aminopeptidase 2, COBALT (II) ION, (E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 53566.00 |
Authors | Eck, M.J.,Song, H.K.,Morollo, A. (deposition date: 2003-09-18, release date: 2003-11-25, Last modification date: 2011-07-13) |
Primary citation | Towbin, H.,Bair, K.W.,DeCaprio, J.A.,Eck, M.J.,Kim, S.,Kinder, F.R.,Morollo, A.,Mueller, D.R.,Schindler, P.,Song, H.K.,van Oostrum, J.,Versace, R.W.,Voshol, H.,Wood, J.,Zabludoff, S.,Phillips, P.E. Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors. J.Biol.Chem., 278:52964-52971, 2003 Cited by PubMed: 14534293DOI: 10.1074/jbc.M309039200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report