1QZY
Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine aminopeptidase 2 | polymer | 478 | 52985.6 | 1 | UniProt (P50579) Pfam (PF00557) | Homo sapiens (human) | MetAP 2, Peptidase M 2, Initiation factor 2 associated 67 kDa glycoprotein, p67, p67eIF2 |
| 2 | B, C (A) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) PubChem (104729) | |||
| 3 | D (A) | (E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE | non-polymer | 388.5 | 1 | Chemie (TDE) PubChem (448235) | |||
| 4 | E (A) | TERTIARY-BUTYL ALCOHOL | non-polymer | 74.1 | 1 | Chemie (TBU) PubChem (6386) | |||
| 5 | F (A) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 1 - 478 (UniProt: P50579)
| PDB | External Database | Details |
|---|---|---|
| Ile 347 | Val 347 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52985.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 580.4 | |
| All* | Total formula weight | 53566.0 |
