2UZH

Mycobacterium smegmatis 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF)

Summary for 2UZH

Entry DOI	10.2210/pdb2uzh/pdb
Descriptor	2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, ZINC ION, CYTIDINE-5'-DIPHOSPHATE, ... (9 entities in total)
Functional Keywords	ispf, lyase, mycobacteria, complex with cdp, non-mevalonate pathway of isoprenoid biosynthesis
Biological source	MYCOBACTERIUM SMEGMATIS
Total number of polymer chains	3
Total formula weight	52600.31
Authors	Buetow, L.,Brown, A.C.,Parish, T.,Hunter, W.N. (deposition date: 2007-04-27, release date: 2007-11-06, Last modification date: 2023-12-13)
Primary citation	Buetow, L.,Brown, A.C.,Parish, T.,Hunter, W.N. The Structure of Mycobacteria 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase, an Essential Enzyme, Provides a Platform for Drug Discovery. Bmc Struct.Biol., 7:68-, 2007 Cited by PubMed: 17956607 DOI: 10.1186/1472-6807-7-68 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation