6U4O

Crystal structure of recombinant class II fumarase from Schistosoma mansoni

Summary for 6U4O

Entry DOI	10.2210/pdb6u4o/pdb
Descriptor	Fumarate hydratase, (2S)-2-hydroxybutanedioic acid, GLYCEROL, ... (5 entities in total)
Functional Keywords	smfhii, fumarate hydratase, lyase
Biological source	Schistosoma mansoni (Blood fluke)
Total number of polymer chains	4
Total formula weight	216480.52
Authors	Cardoso, I.A.,Nonato, M.C. (deposition date: 2019-08-26, release date: 2020-09-02, Last modification date: 2023-10-11)
Primary citation	Cardoso, I.A.,de Souza, A.K.L.,Burgess, A.M.G.,Chalmers, I.W.,Hoffmann, K.F.,Nonato, M.C. Characterization of class II fumarase from Schistosoma mansoni provides the molecular basis for selective inhibition. Int.J.Biol.Macromol., 175:406-421, 2021 Cited by PubMed: 33549669 DOI: 10.1016/j.ijbiomac.2021.01.180 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation