PDB: 2759 件ウェブページステータス検索Chemie searchBIRD

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7EBC	Crystal structure of Isocitrate lyase-1 from Saccaromyces cervisiae 分子名称: Isocitrate lyase, MAGNESIUM ION, TETRAETHYLENE GLYCOL 著者 Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T. 登録日 2021-03-09 公開日 2021-06-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase. J.Struct.Biol., 213, 2021
7EBE	Crystal structure of Isocitrate lyase-1 from Candida albicans 分子名称: FORMIC ACID, Isocitrate lyase, MAGNESIUM ION 著者 Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T. 登録日 2021-03-09 公開日 2021-06-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase. J.Struct.Biol., 213, 2021
2RR0	Structure of epidermal growth factor-like repeat 12 of mouse Notch-1 receptor 分子名称: Neurogenic locus notch homolog protein 1 著者 Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S. 登録日 2010-02-26 公開日 2010-10-13 最終更新日 2024-10-16 実験手法 SOLUTION NMR 主引用文献 Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor J.Am.Chem.Soc., 132, 2010
2RQZ	Structure of sugar modified epidermal growth factor-like repeat 12 of mouse Notch-1 receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, Neurogenic locus notch homolog protein 1 著者 Shimizu, K, Fujitani, N, Hosoguchi, K, Nishimura, S. 登録日 2010-02-26 公開日 2010-10-13 最終更新日 2020-07-29 実験手法 SOLUTION NMR 主引用文献 Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor J.Am.Chem.Soc., 132, 2010
1C5F	CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A 分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1 著者 Ellis, P.J, Carlow, C.K.S, Ma, D, Kuhn, P. 登録日 1999-11-22 公開日 1999-12-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Crystal Structure of the Complex of Brugia Malayi Cyclophilin and Cyclosporin A. Biochemistry, 39, 2000
2YGE	E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin 分子名称: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN, GLYCEROL 著者 Roe, M, Prodromou, C, Pearl, L.H. 登録日 2011-04-14 公開日 2011-11-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.956 Å) 主引用文献 Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise by Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25, 2011
2YGF	L89V, L93I and V136M Mutant of N-Term HSP90 complexed with Geldanamycin 分子名称: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN, GLYCEROL 著者 Roe, M, Prodromou, C, Pearl, L.H. 登録日 2011-04-14 公開日 2011-11-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise by Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25, 2011
4MP4	Crystal structure of a glutathione transferase family member from Acinetobacter baumannii, Target EFI-501785, apo structure 分子名称: Glutathione S-transferase, SULFATE ION 著者 Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2013-09-12 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.498 Å) 主引用文献 Crystal structure of a glutathione transferase family member from Acinetobacter baumannii, Target EFI-501785, apo structure To be Published
4AQL	HUMAN GUANINE DEAMINASE IN COMPLEX WITH VALACYCLOVIR 分子名称: 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate, GUANINE DEAMINASE, ZINC ION 著者 Welin, M, Egeblad, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nyman, T, Persson, C, Schuler, H, Thorsell, A.G, Tresaugues, L, Weigelt, J, Nordlund, P. 登録日 2012-04-18 公開日 2012-05-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Pan-Pathway Based Interaction Profiling of Fda-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism. Plos One, 7, 2012
6POG	Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Wang, J, Pak, J.S, Ozkan, E. 登録日 2019-07-03 公開日 2020-05-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.755 Å) 主引用文献 NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance. Nat Commun, 11, 2020
1IKF	A CONFORMATION OF CYCLOSPORIN A IN AQUEOUS ENVIRONMENT REVEALED BY THE X-RAY STRUCTURE OF A CYCLOSPORIN-FAB COMPLEX 分子名称: CYCLOSPORIN A, IGG1-KAPPA R45-45-11 FAB (HEAVY CHAIN), IGG1-KAPPA R45-45-11 FAB (LIGHT CHAIN) 著者 Vix, O, Altschuh, D, Rees, B, Thierry, J.-C. 登録日 1993-12-09 公開日 1995-03-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Conformation of Cyclosporin a in Aqueous Environment Revealed by the X-Ray Structure of a Cyclosporin-Fab Complex. Science, 256, 1992
4D8Y	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group P212121 at pH 5.6 分子名称: GLYCEROL, Purine nucleoside phosphorylase deoD-type, SULFATE ION 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D8X	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group P6322 at pH 4.6 分子名称: Purine nucleoside phosphorylase deoD-type 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D8V	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis at pH 4.2 分子名称: ADENINE, Purine nucleoside phosphorylase deoD-type, SULFATE ION 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DAE	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 6-chloroguanosine 分子名称: 6-chloro-9-(beta-D-ribofuranosyl)-9H-purin-2-amine, ACETATE ION, CHLORIDE ION, ... 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DAN	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2-fluoroadenosine 分子名称: 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Purine nucleoside phosphorylase deoD-type 著者 Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. 登録日 2012-01-13 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DAB	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with hypoxanthine 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D98	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group H32 at pH 7.5 分子名称: CHLORIDE ION, GLYCEROL, Purine nucleoside phosphorylase deoD-type, ... 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D9H	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with adenosine 分子名称: ADENOSINE, Purine nucleoside phosphorylase deoD-type 著者 Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DA0	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2'-deoxyguanosine 分子名称: 2'-DEOXY-GUANOSINE, CHLORIDE ION, Purine nucleoside phosphorylase deoD-type 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DAO	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with adenine 分子名称: ADENINE, GLYCEROL, Purine nucleoside phosphorylase deoD-type 著者 Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. 登録日 2012-01-13 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DA8	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 8-bromoguanosine 分子名称: 8-bromoguanosine, Purine nucleoside phosphorylase deoD-type 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
2FYP	GRP94 in complex with the novel HSP90 Inhibitor Radester amine 分子名称: 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE, Endoplasmin, PENTAETHYLENE GLYCOL, ... 著者 Immormino, R.M, Gewirth, D.T. 登録日 2006-02-08 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Inhibittory Ligands Adopt Different Conformations When Bound to Hsp90 or GRP94: Implications for Paralog-specific Drug Design To be Published
4DAR	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with tubercidin 分子名称: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Purine nucleoside phosphorylase deoD-type 著者 Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. 登録日 2012-01-13 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4ASB	The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90 分子名称: (4E,6E,8S,9R,10E,12R,13R,14S,16R)-19-{[2-(dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16,21-pentamethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 著者 Roe, S.M, Prodromou, C. 登録日 2012-04-30 公開日 2013-04-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90. Nat Chem, 5, 2013

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