2YGE

E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin

Summary for 2YGE

Entry DOI	10.2210/pdb2yge/pdb
Related	1A4H 1AH6 1AH8 1AM1 1AMW 1BGQ 1HK7 1US7 1USU 1USV 1ZW9 1ZWH 2AKP 2BRC 2BRE 2CG9 2CGE 2CGF 2IWS 2IWU 2IWX 2VW5 2VWC 2WEP 2WEQ 2WER 2XD6 2XX2 2XX4 2XX5 2YGA 2YGF
Descriptor	ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN, GLYCEROL, ... (4 entities in total)
Functional Keywords	chaperone
Biological source	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
Cellular location	Cytoplasm: P02829
Total number of polymer chains	1
Total formula weight	25539.07
Authors	Roe, M.,Prodromou, C.,Pearl, L.H. (deposition date: 2011-04-14, release date: 2011-11-16, Last modification date: 2013-02-06)
Primary citation	Millson, S.H.,Chua, C.S.,Solovieva, S.,Roe, M.,Polier, S.,Pearl, L.H.,Sim, T.S.,Prodromou, C.,Piper, P.W. Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise by Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25:3828-, 2011 Cited by PubMed: 21778327 DOI: 10.1096/FJ.11-188821 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.956 Å)

Structure validation