2YGE
E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 | polymer | 220 | 24886.3 | 1 | UniProt (P02829) Pfam (PF02518) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | 82 KDA HEAT SHOCK PROTEIN, HEAT SHOCK PROTEIN HSP90 HEAT-INDUCIBLE ISOFORM, HSP90 |
| 2 | B (A) | GELDANAMYCIN | non-polymer | 560.6 | 1 | Chemie (GDM) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A: 1 - 220 (UniProt: P02829)
| PDB | External Database | Details |
|---|---|---|
| Arg 44 | Lys 44 | engineered mutation |
| Asn 98 | Lys 98 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24886.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 652.7 | |
| All* | Total formula weight | 25539.1 |
