2RR0
Structure of epidermal growth factor-like repeat 12 of mouse Notch-1 receptor
Summary for 2RR0
| Entry DOI | 10.2210/pdb2rr0/pdb |
| Related | 1TOZ 2JOA 2RQZ 2RR2 |
| Descriptor | Neurogenic locus notch homolog protein 1 (1 entity in total) |
| Functional Keywords | notch, egf-like domain, activator, ank repeat, cell membrane, developmental protein, differentiation, disulfide bond, glycoprotein, metal-binding, notch signaling pathway, nucleus, phosphoprotein, receptor, transcription, transcription regulation, transmembrane |
| Biological source | Mus musculus (MOUSE) |
| Cellular location | Cell membrane; Single-pass type I membrane protein. Notch 1 intracellular domain: Nucleus: Q01705 |
| Total number of polymer chains | 1 |
| Total formula weight | 4218.70 |
| Authors | Hosoguchi, K.,Shimizu, K.,Fujitani, N.,Nishimura, S. (deposition date: 2010-02-26, release date: 2010-10-13, Last modification date: 2011-07-13) |
| Primary citation | Hiruma-Shimizu, K.,Hosoguchi, K.,Liu, Y.,Fujitani, N.,Ohta, T.,Hinou, H.,Matsushita, T.,Shimizu, H.,Feizi, T.,Nishimura, S. Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor J.Am.Chem.Soc., 132:14857-14865, 2010 Cited by PubMed: 20883017DOI: 10.1021/ja105216u PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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