2RQZ
Structure of sugar modified epidermal growth factor-like repeat 12 of mouse Notch-1 receptor
Summary for 2RQZ
Entry DOI | 10.2210/pdb2rqz/pdb |
Related | 1TOZ 2JOA 2RR0 2RR2 |
NMR Information | BMRB: 11006 |
Descriptor | Neurogenic locus notch homolog protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose (2 entities in total) |
Functional Keywords | notch, glycopeptide, o-linked fucose, activator, fringe, ank repeat, developmental protein, differentiation, egf-like domain, glycoprotein, metal-binding, notch signaling pathway, nucleus, phosphorylation, receptor, transcription, transcription regulation, transmembrane, cell membrane, disulfide bond, phosphoprotein |
Biological source | Mus musculus (MOUSE) |
Total number of polymer chains | 1 |
Total formula weight | 4586.05 |
Authors | Shimizu, K.,Fujitani, N.,Hosoguchi, K.,Nishimura, S. (deposition date: 2010-02-26, release date: 2010-10-13, Last modification date: 2020-07-29) |
Primary citation | Hiruma-Shimizu, K.,Hosoguchi, K.,Liu, Y.,Fujitani, N.,Ohta, T.,Hinou, H.,Matsushita, T.,Shimizu, H.,Feizi, T.,Nishimura, S. Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor J.Am.Chem.Soc., 132:14857-14865, 2010 Cited by PubMed: 20883017DOI: 10.1021/ja105216u PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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