2RQZ
Structure of sugar modified epidermal growth factor-like repeat 12 of mouse Notch-1 receptor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00010 |
| Number of Residues | 12 |
| Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. ClDqigeFqCiC |
| Chain | Residue | Details |
| A | CYS16-CYS27 |
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CiCmpGyeGVyC |
| Chain | Residue | Details |
| A | CYS25-CYS36 |
| site_id | PS01186 |
| Number of Residues | 12 |
| Details | EGF_2 EGF-like domain signature 2. CiCmpGYegvy....C |
| Chain | Residue | Details |
| A | CYS25-CYS36 |
| site_id | PS01187 |
| Number of Residues | 25 |
| Details | EGF_CA Calcium-binding EGF-like domain signature. DvNECisnp..........Cqndat..ClDqigeFqC |
| Chain | Residue | Details |
| A | ASP1-CYS25 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Domain: {"description":"EGF-like 12; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q07008","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with DLL4","evidences":[{"source":"UniProtKB","id":"Q07008","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"O-linked (Glc...) serine","evidences":[{"source":"PubMed","id":"21757702","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28089369","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"O-linked (Fuc...) threonine","evidences":[{"source":"PubMed","id":"21757702","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28089369","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
