2JOA

HtrA1 bound to an optimized peptide: NMR assignment of PDZ domain and ligand resonances

Summary for 2JOA

• Entry DOI: 10.2210/pdb2joa/pdb
• Related: 2P3W
• NMR Information: BMRB: 15154
• Descriptor: Serine protease HTRA1, Peptide H1-C1 (2 entities in total)
• Functional Keywords: pdz, beta-sandwich, cyclically-permuted, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 12544.32

Authors

Runyon, S.T.,Zhang, Y.,Appleton, B.A.,Sazinksy, S.L.,Wu, P.,Pan, B.,Wiesmann, C.,Skelton, N.J.,Sidhu, S.S. (deposition date: 2007-03-01, release date: 2007-11-20, Last modification date: 2023-12-20)

• Primary citation: Runyon, S.T.,Zhang, Y.,Appleton, B.A.,Sazinsky, S.L.,Wu, P.,Pan, B.,Wiesmann, C.,Skelton, N.J.,Sidhu, S.S.; Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3; Protein Sci., 16:2454-2471, 2007; PubMed: 17962403; DOI: 10.1110/ps.073049407

Experimental method

SOLUTION NMR