PDB: 433 件ウェブページステータス検索Chemie searchBIRD

---

4II2	Crystal structure of Ubiquitin activating enzyme 1 (Uba1) in complex with the Ub E2 Ubc4, ubiquitin, and ATP/Mg 分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Olsen, S.K, Lima, C.D. 登録日 2012-12-19 公開日 2013-02-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer. Mol.Cell, 49, 2013
4JQU	Crystal structure of Ubc7p in complex with the U7BR of Cue1p 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ... 著者 Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X. 登録日 2013-03-20 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms. Mol.Cell, 50, 2013
2LXP	NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g 分子名称: E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2, ZINC ION 著者 Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. 登録日 2012-08-30 公開日 2013-08-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
2KJH	NMR based structural model of the UBCH8-UBIQUITIN complex 分子名称: Ubiquitin, Ubiquitin/ISG15-conjugating enzyme E2 L6 著者 Serniwka, S.A, Shaw, G.S. 登録日 2009-05-28 公開日 2009-12-08 最終更新日 2024-10-16 実験手法 SOLUTION NMR 主引用文献 The structure of the UbcH8-ubiquitin complex shows a unique ubiquitin interaction site. Biochemistry, 48, 2009
6KL4	Crystal structure of MavC-UBE2N-Ub 分子名称: MavC, Ub, Ubiquitin-conjugating enzyme E2 N 著者 Ouyang, S, Guan, H. 登録日 2019-07-29 公開日 2020-04-15 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC. Adv Sci, 7, 2020
6KG6	Crystal structure of MavC/UBE2N-Ub complex 分子名称: MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N 著者 Wang, Y, Huang, Y, Chang, M, Feng, Y. 登録日 2019-07-10 公開日 2020-04-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC. Nat Commun, 11, 2020
6TTU	Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2 分子名称: CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Prabu, J.R, Schulman, B.A. 登録日 2019-12-30 公開日 2020-02-12 最終更新日 2020-03-04 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly. Nature, 578, 2020
6ULH	Structure of MavC in complex with its substrate in R3 spacegroup 分子名称: LPG2147 (MavC), Ubiquitin, Ubiquitin-conjugating enzyme E2 N 著者 Iyer, S, Puvar, K, Das, C. 登録日 2019-10-08 公開日 2020-05-27 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.968 Å) 主引用文献 Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
6UMS	Crystal structure of MavC in complex with its substrate mimic in C222(1) space group 分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N 著者 Iyer, S, Puvar, K, Das, C. 登録日 2019-10-10 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.344 Å) 主引用文献 Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
6UMP	Crystal structure of MavC in complex with substrate mimic in P65 space group 分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N 著者 Puvar, K, Iyer, S, Luo, Z.Q, Das, C. 登録日 2019-10-10 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
3JVZ	E2~Ubiquitin-HECT 分子名称: E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 著者 Souphron, J, Kamadurai, H.B, Schulman, B.A. 登録日 2009-09-17 公開日 2010-01-12 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Insights into ubiquitin transfer cascades from a structure of a UbcH5B approximately ubiquitin-HECT(NEDD4L) complex. Mol.Cell, 36, 2009
3K9P	The crystal structure of E2-25K and ubiquitin complex 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K 著者 Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. 登録日 2009-10-16 公開日 2010-09-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity J.Biol.Chem., 285, 2010
3L1Z	Crystal structure of the U-BOX domain of human E4B ubiquitin ligase in complex with UBCH5C E2 ubiquitin conjugating enzyme 分子名称: Ubiquitin conjugation factor E4 B, Ubiquitin-conjugating enzyme E2 D3 著者 Benirschke, R, Thompson, J.R, Mer, G. 登録日 2009-12-14 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure, 18, 2010
6M2C	Distinct mechanism of MUL1-RING domain simultaneously recruiting E2 enzyme and the substrate p53-TAD domain 分子名称: Mitochondrial ubiquitin ligase activator of NFKB 1, Ubiquitin-conjugating enzyme E2 D2, ZINC ION 著者 Lee, S.O, Ryu, K.S, Chi, S.-W. 登録日 2020-02-27 公開日 2021-04-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.702 Å) 主引用文献 MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate. Febs J., 2022
6T7F	RCR E3 ligase E2-Ubiquitin transthiolation intermediate 分子名称: 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide, E3 ubiquitin-protein ligase MYCBP2, Polyubiquitin-C, ... 著者 Mabbitt, P.D, Virdee, S. 登録日 2019-10-21 公開日 2020-08-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity. Nat.Chem.Biol., 16, 2020
3K9O	The crystal structure of E2-25K and UBB+1 complex 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K 著者 Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. 登録日 2009-10-16 公開日 2010-09-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis of E2-25K/UBB+1 Interaction for Neurotoxicity of Alzheimer Disease by Proteasome Inhibition To be Published
3JW0	E2~Ubiquitin-HECT 分子名称: E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 著者 Kamadurai, H.B, Schulman, B.A. 登録日 2009-09-17 公開日 2010-01-12 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Insights into ubiquitin transfer cascades from a structure of a UbcH5B approximately ubiquitin-HECT(NEDD4L) complex. Mol.Cell, 36, 2009
6N13	UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin 分子名称: E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ... 著者 Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S. 登録日 2018-11-08 公開日 2018-11-28 最終更新日 2020-01-08 実験手法 SOLUTION NMR 主引用文献 Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation. EMBO J., 37, 2018
6W9D	RNF12 RING domain in complex with a Ube2d2~Ub conjugate 分子名称: E3 ubiquitin-protein ligase RLIM, IODIDE ION, Ubiquitin, ... 著者 Middleton, A.J, Day, C.L. 登録日 2020-03-22 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. J.Mol.Biol., 432, 2020
6LP2	Structure of Lpg2148/UBE2N-Ub complex 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 N, Uncharacterized protein lpg2148 著者 Feng, Y, Wang, Y, Huang, Y, Li, D. 登録日 2020-01-08 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.479 Å) 主引用文献 Structure of Lpg2148/UBE2N-Ub complex To Be Published
6GUM	Structure of the A.thaliana E1 UFD domain in complex with E2 分子名称: GLYCEROL, SAE2, SUMO-conjugating enzyme SCE1 著者 Liu, B, Lois, L.M, Reverter, D. 登録日 2018-06-19 公開日 2019-07-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.792 Å) 主引用文献 Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution. Biochem.J., 476, 2019
5L9U	Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A. 登録日 2016-06-11 公開日 2016-09-14 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell, 165, 2016
2UYZ	Non-covalent complex between Ubc9 and SUMO1 分子名称: SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, SUMO-CONJUGATING ENZYME UBC9 著者 Knipscheer, P, van Dijk, W.J, Olsen, J.V, Mann, M, Sixma, T.K. 登録日 2007-04-21 公開日 2007-06-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation. EMBO J., 26, 2007
6HPR	Crystal structure of cIAP1 RING domain bound to UbcH5B-Ub and a non-covalent Ub 分子名称: Baculoviral IAP repeat-containing protein 2, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Patel, A, Huang, D.T. 登録日 2018-09-21 公開日 2018-12-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex. J. Biol. Chem., 294, 2019
3A4S	The crystal structure of the SLD2:Ubc9 complex 分子名称: NFATC2-interacting protein, SUMO-conjugating enzyme UBC9 著者 Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. 登録日 2009-07-14 公開日 2010-02-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45 Proteins, 78, 2009

<12345678910111213141516>