3L1Z

Crystal structure of the U-BOX domain of human E4B ubiquitin ligase in complex with UBCH5C E2 ubiquitin conjugating enzyme

Summary for 3L1Z

• Entry DOI: 10.2210/pdb3l1z/pdb
• Related: 3L1X 3L1Y
• Descriptor: Ubiquitin-conjugating enzyme E2 D3, Ubiquitin conjugation factor E4 B (3 entities in total)
• Functional Keywords: e4b, ufd2a, ubch5c, u-box ubiquitin ligase, e2 ubiquitin conjugating enzyme, ubl conjugation pathway, ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Peripheral membrane protein: P61077; Cytoplasm (By similarity): O95155
• Total number of polymer chains: 2
• Total formula weight: 29547.58

Authors

Benirschke, R.,Thompson, J.R.,Mer, G. (deposition date: 2009-12-14, release date: 2010-05-05, Last modification date: 2023-09-06)

• Primary citation: Benirschke, R.C.,Thompson, J.R.,Nomine, Y.,Wasielewski, E.,Juranic, N.,Macura, S.,Hatakeyama, S.,Nakayama, K.I.,Botuyan, M.V.,Mer, G.; Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4.; Structure, 18:955-965, 2010; PubMed: 20696396; DOI: 10.1016/j.str.2010.04.017

Experimental method

X-RAY DIFFRACTION (3.17 Å)