PDB: 436 件ウェブページステータス検索Chemie searchBIRD

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2L1Y	NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures 分子名称: Insulin A chain, Insulin B chain 著者 Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A. 登録日 2010-08-09 公開日 2011-08-31 実験手法 SOLUTION NMR 主引用文献 Chiral Protein Engineering and its Application in G Health To be Published
2L1Z	NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures 分子名称: Insulin A chain, Insulin B chain 著者 Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A. 登録日 2010-08-09 公開日 2011-08-31 最終更新日 2020-02-05 実験手法 SOLUTION NMR 主引用文献 Chiral Protein Engineering and its Application in G Health To be Published
2L29	Complex structure of E4 mutant human IGF2R domain 11 bound to IGF-II 分子名称: Insulin-like growth factor 2 receptor variant, Insulin-like growth factor II 著者 Williams, C, Hoppe, H, Rezgui, D, Strickland, M, Frago, S, Ellis, R.Z, Wattana-Amorn, P, Prince, S.N, Zaccheo, O.J, Forbes, B, Jones, E.Y, Crump, M.P, Hassan, A.B. 登録日 2010-08-13 公開日 2012-02-15 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution. Science, 338, 2012
3P2X	Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. 登録日 2010-10-04 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
3P33	Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. 登録日 2010-10-04 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
3Q6E	Human insulin in complex with cucurbit[7]uril 分子名称: Insulin A chain, Insulin B chain, cucurbit[7]uril 著者 Chinai, J.M, Taylor, A.B, Hargreaves, N.D, Ryno, L.M, Morris, C.A, Hart, P.J, Urbach, A.R. 登録日 2010-12-31 公開日 2011-04-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular recognition of insulin by a synthetic receptor. J.Am.Chem.Soc., 133, 2011
3ROV	Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. 登録日 2011-04-26 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus To be Published
3RTO	Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure 分子名称: Insulin, ZINC ION 著者 Soares, A.S, Engel, M.A, Stearns, R, Datwani, S, Olechno, J, Ellson, R, Skinner, J.M, Allaire, M, Orville, A.M. 登録日 2011-05-03 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures. Biochemistry, 50, 2011
3ZQR	NMePheB25 insulin analogue crystal structure 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A. 登録日 2011-06-10 公開日 2011-08-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface. J.Biol.Chem., 286, 2011
3ZS2	TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A. 登録日 2011-06-21 公開日 2011-08-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface. J.Biol.Chem., 286, 2011
3ZU1	Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Schluckebier, G, Whittingham, J. 登録日 2011-07-13 公開日 2011-08-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin To be Published
3T2A	TMAO-grown cubic insulin (porcine) 分子名称: Insulin A chain, Insulin B chain, trimethylamine oxide 著者 Cahn, J, Venkat, M, Marshall, H, Juers, D. 登録日 2011-07-22 公開日 2011-12-28 最終更新日 2012-01-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
2LGB	Modified A22Gly-B31Arg Human Insulin 分子名称: Insulin A chain, Insulin B chain 著者 Bocian, W, Kozerski, L. 登録日 2011-07-25 公開日 2012-04-11 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus. J.Biomol.Nmr, 52, 2012
3TT8	Crystal Structure Analysis of Cu Human Insulin Derivative 分子名称: COPPER (II) ION, INSULIN A-CHAIN, INSULIN B-CHAIN 著者 Prugovecki, B, Matkovic-Calogovic, D. 登録日 2011-09-14 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Crystal Structure Analysis of Cu Human Insulin Derivative To be Published
3U4N	A novel covalently linked insulin dimer 分子名称: Insulin A chain, Insulin B chain 著者 Norrman, M, Vinther, T.N. 登録日 2011-10-10 公開日 2012-04-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization. Plos One, 7, 2012
4A7E	X-ray crystal structure of porcine insulin flash-cooled at high pressure 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Burkhardt, A, Warmer, M, Panneerselvam, S, Wagner, A, Reimer, R, Hohenberg, H, Meents, A. 登録日 2011-11-14 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.856 Å) 主引用文献 Fast High-Pressure Freezing of Protein Crystals in Their Mother Liquor Acta Crystallogr.,Sect.F, 68, 2012
3V19	Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. 登録日 2011-12-09 公開日 2012-12-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health To be Published
3V1G	Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. 登録日 2011-12-09 公開日 2012-12-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health To be Published
4AJX	Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin 分子名称: IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ... 著者 Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. 登録日 2012-02-20 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
4AK0	Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. 登録日 2012-02-21 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
4AJZ	Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. 登録日 2012-02-21 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
4AKJ	Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. 登録日 2012-02-23 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
4E7V	The structure of R6 bovine insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Harris, P, Frankaer, C.G, Knudsen, M.V. 登録日 2012-03-19 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy. Acta Crystallogr.,Sect.D, 68, 2012
4E7T	The structure of T6 bovine insulin 分子名称: Insulin A chain, Insulin B chain, ZINC ION 著者 Harris, P, Frankaer, C.G, Knudsen, M.V. 登録日 2012-03-19 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy. Acta Crystallogr.,Sect.D, 68, 2012
4E7U	The structure of T3R3 bovine insulin 分子名称: Insulin A chain, Insulin B chain, THIOCYANATE ION, ... 著者 Harris, P, Frankaer, C.G, Knudsen, M.V. 登録日 2012-03-19 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy. Acta Crystallogr.,Sect.D, 68, 2012

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