2HOX
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![BU of 2hox by Molmil](/molmil-images/mine/2hox) | alliinase from allium sativum (garlic) | 分子名称: | 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Shimon, L.J.W, Rabinkov, A, Wilcheck, M, Mirelman, D, Frolow, F. | 登録日 | 2006-07-17 | 公開日 | 2007-02-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Two Structures of Alliinase from Alliium sativum L.: Apo Form and Ternary Complex with Aminoacrylate Reaction Intermediate Covalently Bound to the PLP Cofactor. J.Mol.Biol., 366, 2007
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4Z3C
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![BU of 4z3c by Molmil](/molmil-images/mine/4z3c) | Zinc finger region of human TET3 in complex with CpG DNA | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), Methylcytosine dioxygenase, UNKNOWN ATOM OR ION, ... | 著者 | Liu, K, Xu, C, Tempel, W, Dong, A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2015-03-31 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 2017
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1HYH
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7YIX
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![BU of 7yix by Molmil](/molmil-images/mine/7yix) | The Cryo-EM Structure of Human Tissue Nonspecific Alkaline Phosphatase and Single-Chain Fragment Variable (ScFv) Complex. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ... | 著者 | Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y, Qin, A, Ma, P.X, Cao, Y. | 登録日 | 2022-07-18 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase. Nat Commun, 14, 2023
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2H7X
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![BU of 2h7x by Molmil](/molmil-images/mine/2h7x) | Pikromycin Thioesterase adduct with reduced triketide affinity label | 分子名称: | DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ... | 著者 | Giraldes, J.W, Akey, D.L, Kittendorf, J.D, Sherman, D.H, Smith, J.S, Fecik, R.A. | 登録日 | 2006-06-05 | 公開日 | 2006-09-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and Mechanistic Insights of Polyketide Macrolactonization from Polyketide-based Affinity Labels NAT.CHEM.BIOL., 2, 2006
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7XX1
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![BU of 7xx1 by Molmil](/molmil-images/mine/7xx1) | Crystal structure of SARS-CoV-2 N-NTD | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoprotein, ZINC ION | 著者 | Luan, X.D, Li, X.M, Li, Y.F. | 登録日 | 2022-05-27 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein. Sci Bull (Beijing), 67, 2022
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4OJT
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4OJZ
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2GZD
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![BU of 2gzd by Molmil](/molmil-images/mine/2gzd) | Crystal Structure of Rab11 in Complex with Rab11-FIP2 | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab11 family-interacting protein 2, ... | 著者 | Khan, A.R. | 登録日 | 2006-05-11 | 公開日 | 2006-08-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Crystal structure of rab11 in complex with rab11 family interacting protein 2. Structure, 14, 2006
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2VNE
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![BU of 2vne by Molmil](/molmil-images/mine/2vne) | The X-ray structure of Norcoclaurine synthase from Thalictrum flavum | 分子名称: | S-NORCOCLAURINE SYNTHASE | 著者 | Ilari, A, Franceschini, S, Boffi, A, Bonamore, A, Pasquo, A. | 登録日 | 2008-02-04 | 公開日 | 2008-08-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Structural Basis of Enzymatic S-Norcoclaurine Biosynthesis. J.Biol.Chem., 284, 2009
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4O6D
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![BU of 4o6d by Molmil](/molmil-images/mine/4o6d) | West Nile Virus Non-structural protein 1 (NS1) Form 1 crystal | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NS1, ... | 著者 | Akey, D.L, Smith, J.L. | 登録日 | 2013-12-20 | 公開日 | 2014-02-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5936 Å) | 主引用文献 | Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system. Science, 343, 2014
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3TP0
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![BU of 3tp0 by Molmil](/molmil-images/mine/3tp0) | Structural activation of the transcriptional repressor EthR from M. tuberculosis by single amino-acid change mimicking natural and synthetic ligands | 分子名称: | 3-oxo-3-{4-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}propanenitrile, HTH-type transcriptional regulator EthR | 著者 | Carette, X, Blondiaux, N, Willery, E, Hoos, S, Lecat-Guillet, N, Lens, Z, Wohlkonig, A, Wintjens, R, Soror, S, Fr nois, F, Diri, B, Villeret, V, England, P, Lippens, G, Deprez, B, Locht, C, Willand, N, Baulard, A. | 登録日 | 2011-09-07 | 公開日 | 2011-12-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res., 40, 2011
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7Z5C
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![BU of 7z5c by Molmil](/molmil-images/mine/7z5c) | Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R. | 登録日 | 2022-03-09 | 公開日 | 2022-05-11 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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2HV8
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![BU of 2hv8 by Molmil](/molmil-images/mine/2hv8) | Crystal structure of GTP-bound Rab11 in complex with FIP3 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Eathiraj, S, Mishra, A, Prekeris, R, Lambright, D.G. | 登録日 | 2006-07-27 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes. J.Mol.Biol., 364, 2006
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4OTG
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![BU of 4otg by Molmil](/molmil-images/mine/4otg) | Crystal Structure of PRK1 Catalytic Domain in Complex with Lestaurtinib | 分子名称: | Lestaurtinib, Serine/threonine-protein kinase N1 | 著者 | Chamberlain, P.P, Delker, S, Pagarigan, B, Mahmoudi, A, Jackson, P, Abbassian, M, Muir, J, Raheja, N, Cathers, B. | 登録日 | 2014-02-13 | 公開日 | 2014-08-27 | 最終更新日 | 2022-12-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes. Plos One, 9, 2014
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3UQP
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![BU of 3uqp by Molmil](/molmil-images/mine/3uqp) | Crystal structure of Bace1 with its inhibitor | 分子名称: | Beta-secretase 1, METHYL (2R)-1-[(6S,9S,12S,13S,17S,20S,23R)-9-(3-AMINO-3-OXOPROPYL)-12,23-DIBENZYL-13-HYDROXY-2,2,8,20,22-PENTAMETHYL-17-(2-METHYLPROPYL)-4,7,10,15,18,21,24-HEPTAOXO-6-(PROPAN-2-YL)-3-OXA-5,8,11,16,19,22-HEXAAZATETRACOSAN-24-YL]PYRROLIDINE-2-CARBOXYLATE, SULFATE ION | 著者 | Chen, T.T, Chen, W.Y, Li, L, Xu, Y.C. | 登録日 | 2011-11-21 | 公開日 | 2012-11-21 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases J.Med.Chem., 55, 2012
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4CDE
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![BU of 4cde by Molmil](/molmil-images/mine/4cde) | Human DPP1 in complex with 4-amino-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-AZANYL-N-[(2S)-1-AZANYLIDENE-3-[4-(4-CYANOPHENYL)PHENYL]PROPAN-2-YL]OXANE-4-CARBOXAMIDE, CHLORIDE ION, ... | 著者 | Debreczeni, J, Edman, K, Furber, M, Tiden, A, Gardiner, P, Mete, T, Ford, R, Millichip, I, Stein, L, Mather, A, Kinchin, E, Luckhurst, C, Cage, P, Sanghanee, H, Breed, J, Wissler, L. | 登録日 | 2013-10-31 | 公開日 | 2014-03-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate. J.Med.Chem., 57, 2014
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4C2S
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4BQF
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![BU of 4bqf by Molmil](/molmil-images/mine/4bqf) | Arabidopsis thaliana cytosolic alpha-1,4-glucan phosphorylase (PHS2) in complex with acarbose | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC, ... | 著者 | O'Neill, E.C, Rashid, A.M, Stevenson, C.E.M, Hetru, A.C, Gunning, A.P, Rejzek, M, Nepogodiev, S.A, Bornemann, S, Lawson, D.M, Field, R.A. | 登録日 | 2013-05-30 | 公開日 | 2014-02-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Sugar-Coated Sensor Chip and Nanoparticle Surfaces for the in Vitro Enzymatic Synthesis of Starch-Like Materials Chem.Sci., 5, 2014
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7YX1
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4BX9
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![BU of 4bx9 by Molmil](/molmil-images/mine/4bx9) | Human Vps33A in complex with a fragment of human Vps16 | 分子名称: | (2S)-2-hydroxybutanedioic acid, FORMIC ACID, MALONIC ACID, ... | 著者 | Graham, S.C, Wartosch, L, Gray, S.R, Scourfield, E.J, Deane, J.E, Luzio, J.P, Owen, D.J. | 登録日 | 2013-07-09 | 公開日 | 2013-07-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of Vps33A recruitment to the human HOPS complex by Vps16. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
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4BX8
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![BU of 4bx8 by Molmil](/molmil-images/mine/4bx8) | Human Vps33A | 分子名称: | CHLORIDE ION, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A | 著者 | Graham, S.C, Wartosch, L, Gray, S.R, Scourfield, E.J, Deane, J.E, Luzio, J.P, Owen, D.J. | 登録日 | 2013-07-09 | 公開日 | 2013-07-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Basis of Vps33A Recruitment to the Human Hops Complex by Vps16. Proc.Natl.Acad.Sci.USA, 110, 2013
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3GSY
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![BU of 3gsy by Molmil](/molmil-images/mine/3gsy) | Structure of berberine bridge enzyme in complex with dehydroscoulerine | 分子名称: | 2,9-dihydroxy-3,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Winkler, A, Macheroux, P, Gruber, K. | 登録日 | 2009-03-27 | 公開日 | 2009-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine. Phytochemistry, 70, 2009
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4NWN
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![BU of 4nwn by Molmil](/molmil-images/mine/4nwn) | Computationally Designed Two-Component Self-Assembling Tetrahedral Cage T32-28 | 分子名称: | Propanediol utilization: polyhedral bodies pduT, Uncharacterized protein | 著者 | McNamara, D.E, King, N.P, Bale, J.B, Sheffler, W, Baker, D, Yeates, T.O. | 登録日 | 2013-12-06 | 公開日 | 2014-05-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Accurate design of co-assembling multi-component protein nanomaterials. Nature, 510, 2014
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4K5S
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![BU of 4k5s by Molmil](/molmil-images/mine/4k5s) | The crystal structure of premithramycin B in complex with MTMOIV, a baeyer-villiger monooxygenase from the mithramycin biosynthetic pathway in streptomyces argillaceus. | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Oxygenase, premithramycin B | 著者 | Noinaj, N, Bosserman, M.A, Rohr, J, Buchanan, S.K. | 登録日 | 2013-04-15 | 公開日 | 2013-10-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular Insight into Substrate Recognition and Catalysis of Baeyer-Villiger Monooxygenase MtmOIV, the Key Frame-Modifying Enzyme in the Biosynthesis of Anticancer Agent Mithramycin. Acs Chem.Biol., 8, 2013
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