4C2S

Crystal structure of the fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor

Summary for 4C2S

• Entry DOI: 10.2210/pdb4c2s/pdb
• Descriptor: HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, alpha-L-fucopyranose-(1-2)-hexyl 3-deoxy-beta-D-galactopyranoside, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: gta, abo, blood group antigen, glycosylation, transferase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
• Total number of polymer chains: 2
• Total formula weight: 69833.85

Authors

Weadge, J.T.,Palcic, M.,Henriksen, A. (deposition date: 2013-08-19, release date: 2013-09-11, Last modification date: 2023-12-20)

• Primary citation: Weadge, J.T.,Palcic, M.,Henriksen, A.; Structural and Biochemical Characterization of the Human Blood Group a and B Galactosyltransferases Posessing the Pro156Leu Mutation; To be Published,

Experimental method

X-RAY DIFFRACTION (2.48 Å)