7Z5C

Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit

Summary for 7Z5C

Entry DOI	10.2210/pdb7z5c/pdb
EMDB information	14517
Descriptor	AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... (4 entities in total)
Functional Keywords	adaptor complex, ap2, trafficking, clathrin, ccp, protein transport
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	4
Total formula weight	203374.82
Authors	Kane Dickson, V.,Qu, K.,Owen, D.J.,Briggs, J.A.,Zaccai, N.R. (deposition date: 2022-03-09, release date: 2022-05-11)
Primary citation	Zaccai, N.R.,Kadlecova, Z.,Dickson, V.K.,Korobchevskaya, K.,Kamenicky, J.,Kovtun, O.,Umasankar, P.K.,Wrobel, A.G.,Kaufman, J.G.G.,Gray, S.R.,Qu, K.,Evans, P.R.,Fritzsche, M.,Sroubek, F.,Honing, S.,Briggs, J.A.G.,Kelly, B.T.,Owen, D.J.,Traub, L.M. FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8:eabn2018-eabn2018, 2022 Cited by PubMed: 35486718 DOI: 10.1126/sciadv.abn2018 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.16 Å)

Structure validation