2H7X
Pikromycin Thioesterase adduct with reduced triketide affinity label
Summary for 2H7X
Entry DOI | 10.2210/pdb2h7x/pdb |
Related | 1MNA 2H7Y |
Descriptor | Type I polyketide synthase PikAIV, SULFATE ION, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | thioesterase, alpha-beta hydrolase, hydrolase |
Biological source | Streptomyces venezuelae |
Total number of polymer chains | 2 |
Total formula weight | 68468.73 |
Authors | Giraldes, J.W.,Akey, D.L.,Kittendorf, J.D.,Sherman, D.H.,Smith, J.S.,Fecik, R.A. (deposition date: 2006-06-05, release date: 2006-09-19, Last modification date: 2023-08-30) |
Primary citation | Giraldes, J.W.,Akey, D.L.,Kittendorf, J.D.,Sherman, D.H.,Smith, J.S.,Fecik, R.A. Structural and Mechanistic Insights of Polyketide Macrolactonization from Polyketide-based Affinity Labels NAT.CHEM.BIOL., 2:531-536, 2006 Cited by PubMed: 16969373DOI: 10.1038/nchembio822 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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