3GSY

Structure of berberine bridge enzyme in complex with dehydroscoulerine

Summary for 3GSY

Entry DOI	10.2210/pdb3gsy/pdb
Related	3D2D 3D2H 3D2J 3FW7 3FW8 3FW9
Descriptor	Reticuline oxidase; Berberine bridge-forming enzyme, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... (7 entities in total)
Functional Keywords	complex with dehydroscoulerine, bicovalent flavinylation, n-glycosylation, p-cresol methyl hydroxylase superfamily, alkaloid metabolism, cytoplasmic vesicle, fad, flavoprotein, glycoprotein, oxidoreductase
Biological source	Eschscholzia californica (California poppy)
Cellular location	Cytoplasmic vesicle: P30986
Total number of polymer chains	1
Total formula weight	59817.28
Authors	Winkler, A.,Macheroux, P.,Gruber, K. (deposition date: 2009-03-27, release date: 2009-06-30, Last modification date: 2023-09-06)
Primary citation	Winkler, A.,Puhl, M.,Weber, H.,Kutchan, T.M.,Gruber, K.,Macheroux, P. Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine. Phytochemistry, 70:1092-1097, 2009 Cited by PubMed: 19570558 DOI: 10.1016/j.phytochem.2009.06.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.63 Å)

Structure validation