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6GZ6
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Structure of a left-handed G-quadruplex
分子名称: DNA (27-MER), POTASSIUM ION
著者Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T.
登録日2018-07-03
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew.Chem.Int.Ed.Engl., 58, 2019
6D37
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BU of 6d37 by Molmil
Trp-cage tr16b R16Nva : Elimination of pH Dependent Interactions
分子名称: ALA-TYR-ALA-GLN-TRP-LEU-ALA-ASP-DAL-GLY-PRO-ALA-SER-DAL-NVA-PRO-PRO-PRO-SER
著者Byrne, A, Andersen, N.H.
登録日2018-04-14
公開日2019-03-13
最終更新日2019-12-04
実験手法SOLUTION NMR
主引用文献Reversing the typical pH stability profile of the Trp-cage.
Biopolymers, 110, 2019
6CVO
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BU of 6cvo by Molmil
Human Aprataxin (Aptx) bound to nicked RNA-DNA, AMP and Zn product complex
分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ...
著者Schellenberg, M.J, Tumbale, P.P, Williams, R.S.
登録日2018-03-28
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease.
EMBO J., 37, 2018
6GB1
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BU of 6gb1 by Molmil
Crystal structure of the GLP1 receptor ECD with Peptide 11
分子名称: Glucagon-like peptide 1 receptor, HEXANE-1,6-DIOL, Peptide 11, ...
著者Schreuder, H.A, Liesum, A.
登録日2018-04-13
公開日2018-06-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
J. Med. Chem., 61, 2018
6GBM
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BU of 6gbm by Molmil
Solution structure of FUS-RRM bound to stem-loop RNA
分子名称: RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS
著者Loughlin, F.E, Allain, F.H.-T.
登録日2018-04-15
公開日2019-02-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol. Cell, 73, 2019
6CGX
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BU of 6cgx by Molmil
Backbone cyclised conotoxin Vc1.1 mutant - D11A, E14A
分子名称: Alpha-conotoxin Vc1A
著者Clark, R.J.
登録日2018-02-21
公開日2018-05-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by alpha-Conotoxin Vc1.1.
ACS Chem. Biol., 13, 2018
6COQ
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BU of 6coq by Molmil
CSP1-K6A
分子名称: Competence-stimulating peptide type 1
著者Yang, Y.
登録日2018-03-12
公開日2018-08-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Characterization of Competence-Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumoniae.
Biochemistry, 57, 2018
6G4J
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BU of 6g4j by Molmil
Structure of the protein kinase YabT from Bacillus subtilis in complex with an alphaREP crystallization helper
分子名称: Probable serine/threonine-protein kinase YabT, alphaREP bE8
著者Nessler, S, Cavagnino, A, Rabefiraisana, J.L.
登録日2018-03-27
公開日2019-01-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Structural Analysis of the Hanks-Type Protein Kinase YabT FromBacillus subtilisProvides New Insights in its DNA-Dependent Activation.
Front Microbiol, 9, 2018
6COP
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BU of 6cop by Molmil
CSP1-R3A
分子名称: Competence-stimulating peptide type 1
著者Yang, Y.
登録日2018-03-12
公開日2018-08-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Characterization of Competence-Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumoniae.
Biochemistry, 57, 2018
6BZL
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BU of 6bzl by Molmil
Solution structure of VEK75
分子名称: M protein
著者Qiu, C, Yuan, Y, Castellino, F.J.
登録日2017-12-24
公開日2019-01-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization.
J.Struct.Biol., 204, 2018
6BPU
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BU of 6bpu by Molmil
Crystal structure of ferrous form of the F2-Tyr157 human cysteine dioxygenase with both uncrosslinked and crosslinked cofactor
分子名称: Cysteine dioxygenase type 1, FE (II) ION, GLYCEROL, ...
著者Liu, A, Li, J, Shin, I.
登録日2017-11-26
公開日2018-07-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase.
Nat. Chem. Biol., 14, 2018
6GWS
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BU of 6gws by Molmil
Crystal structure of human PCNA in complex with three p15 peptides
分子名称: PCNA-associated factor, Proliferating cell nuclear antigen
著者De March, M, Merino, N, Gonzalez-Magana, A, Romano-Moreno, M, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2018-06-25
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
6D74
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BU of 6d74 by Molmil
Direct Activation of the Executioner Domain of MLKL by a Select Repertoire of Inositol Phosphates
分子名称: Mixed lineage kinase domain-like protein
著者Royappa, G.C, McNamara, D.E, Moldoveanu, T.
登録日2018-04-24
公開日2019-05-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
Cell Chem Biol, 26, 2019
6H5T
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BU of 6h5t by Molmil
Intersectin SH3A short isoform
分子名称: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, ACETATE ION, CHLORIDE ION, ...
著者Driller, J.H, Gerth, F, Freund, C, Wahl, M.C, Loll, B.
登録日2018-07-25
公開日2019-02-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.689 Å)
主引用文献Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain.
Structure, 27, 2019
6GXG
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BU of 6gxg by Molmil
Tryparedoxin from Trypanosoma brucei in complex with CFT
分子名称: 5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one, GLYCEROL, Tryparedoxin
著者Bader, N, Wagner, A, Hellmich, U, Schindelin, H.
登録日2018-06-27
公開日2019-01-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes.
Angew. Chem. Int. Ed. Engl., 58, 2019
6DFA
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BU of 6dfa by Molmil
Kaiso (ZBTB33) E535A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.908 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6GXZ
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BU of 6gxz by Molmil
Crystal structure of the human RPAP3(TPR2)-PIH1D1(CS) complex
分子名称: CALCIUM ION, PIH1 domain-containing protein 1, RNA polymerase II-associated protein 3
著者Henri, J, Quinternet, M, Manival, X, Chagot, M.-E, Charpentier, B, Meyer, P.
登録日2018-06-27
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.965 Å)
主引用文献Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.
Structure, 26, 2018
6GIS
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BU of 6gis by Molmil
Structural basis of human clamp sliding on DNA
分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen
著者De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2018-05-15
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
6CMS
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BU of 6cms by Molmil
Closed structure of active SHP2 mutant E76K bound to SHP099 inhibitor
分子名称: 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11
著者Padua, R.A.P, Sun, Y, Marko, I, Pitsawong, W, Kern, D.
登録日2018-03-06
公開日2018-11-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2.
Nat Commun, 9, 2018
6COT
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BU of 6cot by Molmil
CSP2-d10
分子名称: Competence-stimulating peptide type 2
著者Yang, Y.
登録日2018-03-12
公開日2018-08-29
最終更新日2018-09-19
実験手法SOLUTION NMR
主引用文献Structural Characterization of Competence-Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumoniae.
Biochemistry, 57, 2018
6CBI
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BU of 6cbi by Molmil
PCNA in complex with inhibitor
分子名称: GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, Proliferating cell nuclear antigen, SULFATE ION
著者Bruning, J.B, Wegener, K.L.
登録日2018-02-03
公開日2018-07-04
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CCI
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BU of 6cci by Molmil
The Crystal Structure of XOAT1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Alahuhta, P.M, Lunin, V.V.
登録日2018-02-07
公開日2019-02-20
最終更新日2020-09-02
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular Mechanism of Polysaccharide Acetylation by the Arabidopsis XylanO-acetyltransferase XOAT1.
Plant Cell, 32, 2020
6GKG
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BU of 6gkg by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser164
分子名称: 14-3-3 protein gamma, Caspase-2
著者Alblova, M, Obsil, T, Obsilova, V.
登録日2018-05-20
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.847 Å)
主引用文献14-3-3 protein masks the nuclear localization sequence of caspase-2.
FEBS J., 285, 2018
6AXJ
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BU of 6axj by Molmil
Crystal structure of the Yaf9 YEATS domain bound to H3K27ac
分子名称: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ...
著者Klein, B.J, Kutateladze, T.G.
登録日2017-09-06
公開日2017-11-22
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.379 Å)
主引用文献Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
6AVI
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BU of 6avi by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Nonanoic acid
分子名称: 2-chloro-5-nitro-N-phenylbenzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid
著者Shang, J, Kojetin, D.J.
登録日2017-09-02
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018

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