6BPU

Crystal structure of ferrous form of the F2-Tyr157 human cysteine dioxygenase with both uncrosslinked and crosslinked cofactor

Summary for 6BPU

DescriptorCysteine dioxygenase type 1, FE (II) ION, SULFATE ION, ... (5 entities in total)
Functional Keywordscysteine, cys-tyr cofactor, iron, unnatural amino acid, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight23694.15
Authors
Liu, A.,Li, J.,Shin, I. (deposition date: 2017-11-26, release date: 2018-07-04, Last modification date: 2019-11-27)
Primary citation
Li, J.,Griffith, W.P.,Davis, I.,Shin, I.,Wang, J.,Li, F.,Wang, Y.,Wherritt, D.J.,Liu, A.
Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase.
Nat. Chem. Biol., 14:853-860, 2018
PubMed: 29942080 (PDB entries with the same primary citation)
DOI: 10.1038/s41589-018-0085-5
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.18840 0.6% 3.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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167518
PDB entries from 2020-08-12