6CBI
PCNA in complex with inhibitor
Summary for 6CBI
Entry DOI | 10.2210/pdb6cbi/pdb |
Descriptor | Proliferating cell nuclear antigen, GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, SULFATE ION, ... (4 entities in total) |
Functional Keywords | pcna, sliding clamp, proliferating cell nuclear antigen, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 180170.88 |
Authors | Bruning, J.B.,Wegener, K.L. (deposition date: 2018-02-03, release date: 2018-07-04, Last modification date: 2020-01-29) |
Primary citation | Wegener, K.L.,McGrath, A.E.,Dixon, N.E.,Oakley, A.J.,Scanlon, D.B.,Abell, A.D.,Bruning, J.B. Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp. Chemistry, 24:11325-11331, 2018 Cited by PubMed: 29917264DOI: 10.1002/chem.201801734 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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