PCNA in complex with inhibitor

Summary for 6CBI

DescriptorProliferating cell nuclear antigen, GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, SULFATE ION, ... (4 entities in total)
Functional Keywordspcna, sliding clamp, proliferating cell nuclear antigen, cell cycle
Biological sourceHomo sapiens (Human)
Total number of polymer chains10
Total molecular weight180170.88
Bruning, J.B.,Wegener, K.L. (deposition date: 2018-02-03, release date: 2018-07-04, Last modification date: 2020-01-29)
Primary citation
Wegener, K.L.,McGrath, A.E.,Dixon, N.E.,Oakley, A.J.,Scanlon, D.B.,Abell, A.D.,Bruning, J.B.
Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24:11325-11331, 2018
PubMed: 29917264 (PDB entries with the same primary citation)
DOI: 10.1002/chem.201801734
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25411 1.2% 6.8% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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