6CGX

Backbone cyclised conotoxin Vc1.1 mutant - D11A, E14A

Summary for 6CGX

• Entry DOI: 10.2210/pdb6cgx/pdb
• NMR Information: BMRB: 30412
• Descriptor: Alpha-conotoxin Vc1A (1 entity in total)
• Functional Keywords: structure from molmol, toxin
• Biological source: Conus victoriae (Queen Victoria cone)
• Total number of polymer chains: 1
• Total formula weight: 2082.33

Authors

Clark, R.J. (deposition date: 2018-02-21, release date: 2018-05-23, Last modification date: 2023-06-14)

• Primary citation: Sadeghi, M.,Carstens, B.B.,Callaghan, B.P.,Daniel, J.T.,Tae, H.S.,O'Donnell, T.,Castro, J.,Brierley, S.M.,Adams, D.J.,Craik, D.J.,Clark, R.J.; Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by alpha-Conotoxin Vc1.1.; ACS Chem. Biol., 13:1577-1587, 2018; PubMed: 29746088; DOI: 10.1021/acschembio.8b00190

Experimental method

SOLUTION NMR