6GWS

Crystal structure of human PCNA in complex with three p15 peptides

Summary for 6GWS

DescriptorProliferating cell nuclear antigen, PCNA-associated factor (3 entities in total)
Functional Keywordspcna, p15, p15paf, paf15, crystal, complex, replication, dna repair.
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total molecular weight98190.83
Authors
De March, M.,Merino, N.,Gonzalez-Magana, A.,Romano-Moreno, M.,Onesti, S.,Blanco, F.J.,De Biasio, A. (deposition date: 2018-06-25, release date: 2018-08-22, Last modification date: 2018-10-24)
Primary citation
De March, M.,Barrera-Vilarmau, S.,Crespan, E.,Mentegari, E.,Merino, N.,Gonzalez-Magana, A.,Romano-Moreno, M.,Maga, G.,Crehuet, R.,Onesti, S.,Blanco, F.J.,De Biasio, A.
p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46:9816-9828, 2018
PubMed: 30102405 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gky723
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26722 0.2% 5.4% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6gws
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Molmil generated image of 6gws
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Molmil generated image of 6gws
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