4DM8
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![BU of 4dm8 by Molmil](/molmil-images/mine/4dm8) | Crystal structure of RARb LBD in complex with 9cis retinoic acid | 分子名称: | Nuclear receptor coactivator 1, RETINOIC ACID, Retinoic acid receptor beta | 著者 | Osz, J, Br livet, Y, Peluso-Iltis, C, Cura, V, Eiler, S, Ruff, M, Bourguet, W, Rochel, N, Moras, D. | 登録日 | 2012-02-07 | 公開日 | 2012-03-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors. Proc.Natl.Acad.Sci.USA, 109, 2012
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4C31
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![BU of 4c31 by Molmil](/molmil-images/mine/4c31) | Nup1:Sac3:Sus1 complex | 分子名称: | NUCLEAR MRNA EXPORT PROTEIN SAC3, NUCLEOPORIN NUP1, PROTEIN SUS1 | 著者 | Stewart, M, Jani, D. | 登録日 | 2013-08-21 | 公開日 | 2014-04-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Basis for Binding the Trex2 Complex to Nuclear Pores, Gal1 Localisation and Mrna Export. Nucleic Acids Res., 42, 2014
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7AT8
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![BU of 7at8 by Molmil](/molmil-images/mine/7at8) | Histone H3 recognition by nucleosome-bound PRC2 subunit EZH2. | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3.2, ... | 著者 | Finogenova, K, Benda, C, Schaefer, I.B, Poepsel, S, Strauss, M, Mueller, J. | 登録日 | 2020-10-29 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3. Elife, 9, 2020
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1RZR
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![BU of 1rzr by Molmil](/molmil-images/mine/1rzr) | crystal structure of transcriptional regulator-phosphoprotein-DNA complex | 分子名称: | 5'-D(*CP*TP*GP*AP*AP*AP*GP*CP*GP*CP*TP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*AP*GP*CP*GP*CP*TP*TP*TP*CP*AP*G)-3', Glucose-resistance amylase regulator, ... | 著者 | Schumacher, M.A, Allen, G.S, Brennan, R.G. | 登録日 | 2003-12-27 | 公開日 | 2004-10-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P. Cell(Cambridge,Mass.), 118, 2004
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4DM6
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![BU of 4dm6 by Molmil](/molmil-images/mine/4dm6) | Crystal structure of RARb LBD homodimer in complex with TTNPB | 分子名称: | 4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID, Nuclear receptor coactivator 1, Retinoic acid receptor beta | 著者 | Osz, J, Brelivet, Y, Peluso-Iltis, C, Cura, V, Eiler, S, Ruff, M, Bourguet, W, Rochel, N, Moras, D. | 登録日 | 2012-02-07 | 公開日 | 2012-03-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors. Proc.Natl.Acad.Sci.USA, 109, 2012
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6SWA
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![BU of 6swa by Molmil](/molmil-images/mine/6swa) | |
8JHO
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![BU of 8jho by Molmil](/molmil-images/mine/8jho) | |
8JAR
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![BU of 8jar by Molmil](/molmil-images/mine/8jar) | Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAL
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![BU of 8jal by Molmil](/molmil-images/mine/8jal) | Structure of CRL2APPBP2 bound with RxxGP degron (dimer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-06 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAQ
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![BU of 8jaq by Molmil](/molmil-images/mine/8jaq) | Structure of CRL2APPBP2 bound with RxxGP degron (tetramer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-06 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAS
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![BU of 8jas by Molmil](/molmil-images/mine/8jas) | Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAU
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![BU of 8jau by Molmil](/molmil-images/mine/8jau) | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (dimer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAV
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![BU of 8jav by Molmil](/molmil-images/mine/8jav) | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer) | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Zhao, S, Zhang, K, Xu, C. | 登録日 | 2023-05-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8OF4
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![BU of 8of4 by Molmil](/molmil-images/mine/8of4) | Nucleosome Bound human SIRT6 (Composite) | 分子名称: | DNA (145-MER), Histone H2A type 1, Histone H2B, ... | 著者 | Smirnova, E, Bignon, E, Schultz, P, Papai, G, Ben-Shem, A. | 登録日 | 2023-03-13 | 公開日 | 2023-08-09 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Binding to nucleosome poises human SIRT6 for histone H3 deacetylation. Elife, 12, 2024
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6VIL
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![BU of 6vil by Molmil](/molmil-images/mine/6vil) | |
6W4K
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![BU of 6w4k by Molmil](/molmil-images/mine/6w4k) | Crystal structure of Lysine Specific Demethylase 1 (LSD1) with CC-90011 | 分子名称: | 4-[2-(4-aminopiperidin-1-yl)-5-(3-fluoro-4-methoxyphenyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-4-yl]-2-fluorobenzonitrile, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, ... | 著者 | Hosfield, D.J. | 登録日 | 2020-03-11 | 公開日 | 2020-10-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1). J.Med.Chem., 63, 2020
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3TX7
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![BU of 3tx7 by Molmil](/molmil-images/mine/3tx7) | Crystal structure of LRH-1/beta-catenin complex | 分子名称: | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Catenin beta-1, Nuclear receptor subfamily 5 group A member 2 | 著者 | Yumoto, F, Fletterick, R. | 登録日 | 2011-09-22 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural basis of coactivation of liver receptor homolog-1 by beta-catenin. Proc.Natl.Acad.Sci.USA, 109, 2012
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4CZZ
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![BU of 4czz by Molmil](/molmil-images/mine/4czz) | Histone demethylase LSD1(KDM1A)-CoREST3 Complex | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 3 | 著者 | Barrios, A.P, Gomez, A.V, Saez, J.E, Ciossani, G, Toffolo, E, Battaglioli, E, Mattevi, A, Andres, M.E. | 登録日 | 2014-04-23 | 公開日 | 2014-06-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Differential Properties of Transcriptional Complexes Formed by the Corest Family. Mol.Cell.Biol., 34, 2014
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1K0D
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![BU of 1k0d by Molmil](/molmil-images/mine/1k0d) | Ure2p in Complex with Glutathione | 分子名称: | GLUTATHIONE, URE2 PROTEIN | 著者 | Bousset, L, Belrhali, H, Melki, R, Morera, S. | 登録日 | 2001-09-19 | 公開日 | 2001-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. Biochemistry, 40, 2001
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1JZR
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![BU of 1jzr by Molmil](/molmil-images/mine/1jzr) | Ure2p in complex with glutathione | 分子名称: | GLUTATHIONE, URE2 PROTEIN | 著者 | Bousset, L, Belrhali, H, Melki, R, Morera, S. | 登録日 | 2001-09-17 | 公開日 | 2001-12-21 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. Biochemistry, 40, 2001
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1MM2
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![BU of 1mm2 by Molmil](/molmil-images/mine/1mm2) | Solution structure of the 2nd PHD domain from Mi2b | 分子名称: | Mi2-beta, ZINC ION | 著者 | Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. | 登録日 | 2002-09-02 | 公開日 | 2003-07-22 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
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2W0X
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![BU of 2w0x by Molmil](/molmil-images/mine/2w0x) | FACTOR INHIBITING HIF-1 ALPHA WITH PYRIDINE 2,4 DICARBOXYLIC ACID | 分子名称: | FE (II) ION, GLYCEROL, HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR, ... | 著者 | Conejo-Garcia, A, Lienard, B.M.R, Clifton, I.J, McDonough, M.A, Schofield, C.J. | 登録日 | 2008-10-10 | 公開日 | 2009-11-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor. Bioorg. Med. Chem. Lett., 20, 2010
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5FXY
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![BU of 5fxy by Molmil](/molmil-images/mine/5fxy) | Structure of the human RBBP4:MTA1(464-546) complex | 分子名称: | HISTONE-BINDING PROTEIN RBBP4, METASTASIS-ASSOCIATED PROTEIN MTA1 | 著者 | Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R. | 登録日 | 2016-03-03 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The structure of the core NuRD repression complex provides insights into its interaction with chromatin. Elife, 5, 2016
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6KZ5
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![BU of 6kz5 by Molmil](/molmil-images/mine/6kz5) | Crystal Structure Analysis of the Csn-B-bounded NUR77 Ligand binding Domain | 分子名称: | Nuclear receptor subfamily 4 group A member 1, ethyl 2-[2-octanoyl-3,5-bis(oxidanyl)phenyl]ethanoate | 著者 | Hong, W, Chen, H, Wu, Q, Lin, T. | 登録日 | 2019-09-23 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (4.45 Å) | 主引用文献 | Blocking PPAR gamma interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression. Proc.Natl.Acad.Sci.USA, 117, 2020
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2WA3
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![BU of 2wa3 by Molmil](/molmil-images/mine/2wa3) | FACTOR INHIBITING HIF-1 ALPHA WITH 2-(3-hydroxyphenyl)-2-oxoacetic acid | 分子名称: | 2-(3-HYDROXYPHENYL)-2-OXO-ETHANOIC ACID, FE (II) ION, HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR | 著者 | Conejo-Garcia, A, Lienard, B.M.R, Clifton, I.J, McDonough, M.A, Schofield, C.J. | 登録日 | 2009-02-02 | 公開日 | 2010-04-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor. Bioorg. Med. Chem. Lett., 20, 2010
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