8JAR

Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer)

Summary for 8JAR

• Entry DOI: 10.2210/pdb8jar/pdb
• EMDB information: 36132
• Descriptor: Amyloid protein-binding protein 2, Elongin-B, Elongin-C, ... (6 entities in total)
• Functional Keywords: e3 ubiquitination ligase, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 358757.16

Authors

Zhao, S.,Zhang, K.,Xu, C. (deposition date: 2023-05-07, release date: 2023-10-18, Last modification date: 2023-10-25)

• Primary citation: Zhao, S.,Olmayev-Yaakobov, D.,Ru, W.,Li, S.,Chen, X.,Zhang, J.,Yao, X.,Koren, I.,Zhang, K.,Xu, C.; Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.; Proc.Natl.Acad.Sci.USA, 120:e2308870120-e2308870120, 2023; PubMed: 37844242; DOI: 10.1073/pnas.2308870120

Experimental method

ELECTRON MICROSCOPY (3.3 Å)