8OF4
Nucleosome Bound human SIRT6 (Composite)
Summary for 8OF4
Entry DOI | 10.2210/pdb8of4/pdb |
EMDB information | 16842 16843 16845 16861 |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (8 entities in total) |
Functional Keywords | transferase, deacetylase, histone h3 deacetylation, gene regulation |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 11 |
Total formula weight | 238534.87 |
Authors | Smirnova, E.,Bignon, E.,Schultz, P.,Papai, G.,Ben-Shem, A. (deposition date: 2023-03-13, release date: 2023-08-09, Last modification date: 2024-03-13) |
Primary citation | Smirnova, E.,Bignon, E.,Schultz, P.,Papai, G.,Ben Shem, A. Binding to nucleosome poises human SIRT6 for histone H3 deacetylation. Elife, 12:-, 2024 Cited by PubMed: 38415718DOI: 10.7554/eLife.87989 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.94 Å) |
Structure validation
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