4DM8
Crystal structure of RARb LBD in complex with 9cis retinoic acid
Summary for 4DM8
Entry DOI | 10.2210/pdb4dm8/pdb |
Related | 1XAP 4DM6 4DMA |
Descriptor | Retinoic acid receptor beta, Nuclear receptor coactivator 1, RETINOIC ACID, ... (4 entities in total) |
Functional Keywords | nuclear receptor, rarb, 9cis retinoic acid, alpha helical sandwich, transcription factor, retinoic acid, transcription-protein binding complex, transcription/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform Beta-1: Nucleus. Isoform Beta-2: Nucleus. Isoform Beta-4: Cytoplasm: P10826 Nucleus : Q15788 |
Total number of polymer chains | 4 |
Total formula weight | 66571.12 |
Authors | Osz, J.,Br livet, Y.,Peluso-Iltis, C.,Cura, V.,Eiler, S.,Ruff, M.,Bourguet, W.,Rochel, N.,Moras, D. (deposition date: 2012-02-07, release date: 2012-03-07, Last modification date: 2024-02-28) |
Primary citation | Osz, J.,Brelivet, Y.,Peluso-Iltis, C.,Cura, V.,Eiler, S.,Ruff, M.,Bourguet, W.,Rochel, N.,Moras, D. Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors. Proc.Natl.Acad.Sci.USA, 109:E588-E594, 2012 Cited by PubMed: 22355136DOI: 10.1073/pnas.1118192109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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