1XAP

Structure of the ligand binding domain of the Retinoic Acid Receptor beta

Summary for 1XAP

Entry DOI	10.2210/pdb1xap/pdb
Descriptor	Retinoic acid receptor beta, 4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID (3 entities in total)
Functional Keywords	nuclear receptor, ligand binding domain, retinoic acid receptor beta, ttnpb, transcription
Biological source	Homo sapiens (human)
Cellular location	Isoform Beta-1: Nucleus. Isoform Beta-2: Nucleus. Isoform Beta-4: Cytoplasm: P10826
Total number of polymer chains	1
Total formula weight	30527.44
Authors	Germain, P.,Kammerer, S.,Peluso-Iltis, C.,Tortolani, D.,Zusi, F.C.,Starrett, J.,Lapointe, P.,Daris, J.P.,Marinier, A.,De Lera, A.R.,Rochel, N.,Gronemeyer, H. (deposition date: 2004-08-26, release date: 2004-11-16, Last modification date: 2023-10-25)
Primary citation	Germain, P.,Kammerer, S.,Perez, E.,Peluso-Iltis, C.,Tortolani, D.,Zusi, F.C.,Starrett, J.,Lapointe, P.,Daris, J.P.,Marinier, A.,De Lera, A.R.,Rochel, N.,Gronemeyer, H. Rational design of RAR-selective ligands revealed by RARbeta crystal structure Embo Rep., 5:877-882, 2004 Cited by PubMed: 15319780 DOI: 10.1038/sj.embor.7400235 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation