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4LL5
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BU of 4ll5 by Molmil
Crystal Structure of Pim-1 in complex with the fluorescent compound SKF86002
分子名称: 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole, CALCIUM ION, GLYCEROL, ...
著者Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S.
登録日2013-07-09
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
4LLI
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BU of 4lli by Molmil
Crystal Structure of human Myosin 5a globular domain
分子名称: Unconventional myosin-Va
著者Velvarska, H, Niessing, D.
登録日2013-07-09
公開日2013-12-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into the globular tails of the human type v myosins myo5a, myo5b, and myo5c.
Plos One, 8, 2013
4LIJ
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Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution
分子名称: Far upstream element-binding protein 1, PHOSPHATE ION
著者Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology, Partnership for T-Cell Biology (TCELL)
登録日2013-07-02
公開日2013-11-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution
To be published
4LJZ
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BU of 4ljz by Molmil
Crystal Structure Analysis of the E.coli holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5871 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LDF
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BU of 4ldf by Molmil
Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190
分子名称: GCN5 like acetylase + bromodomain, GLYCEROL, UNKNOWN ATOM OR ION
著者Wernimont, A.K, Loppnau, P, Fonseca, M, Knapp, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Mottaghi, K, Structural Genomics Consortium (SGC)
登録日2013-06-24
公開日2013-07-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190
TO BE PUBLISHED
4LDZ
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BU of 4ldz by Molmil
Crystal structure of the full-length response regulator DesR in the active state
分子名称: BERYLLIUM TRIFLUORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Trajtenberg, F, Larrieux, N, Buschiazzo, A.
登録日2013-06-25
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
4WF7
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BU of 4wf7 by Molmil
Crystal structures of trehalose synthase from Deinococcus radiodurans reveal that a closed conformation is involved in the intramolecular isomerization catalysis
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, MAGNESIUM ION, ...
著者Wang, Y.L, Chow, S.Y, Lin, Y.T, Hsieh, Y.C, Lee, G.C, Liaw, S.H.
登録日2014-09-13
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structures of trehalose synthase from Deinococcus radiodurans reveal that a closed conformation is involved in catalysis of the intramolecular isomerization.
Acta Crystallogr.,Sect.D, 70, 2014
4LEK
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BU of 4lek by Molmil
Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines
分子名称: 7-[5,6-dimethoxy-2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]quinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.T.
登録日2013-06-25
公開日2014-02-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines.
J.Med.Chem., 57, 2014
4WHD
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BU of 4whd by Molmil
Human CEACAM1 N-domain homodimer
分子名称: Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, octyl beta-D-glucopyranoside
著者Kirouac, K.N, Prive, G.G.
登録日2014-09-22
公開日2015-10-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human CEACAM1 N-domain homodimer
To Be Published
4LK9
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BU of 4lk9 by Molmil
Crystal Structure of MOZ double PHD finger histone H3 tail complex
分子名称: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION
著者Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M.
登録日2013-07-07
公開日2013-10-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
4LKM
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BU of 4lkm by Molmil
Crystal structure of Plk1 Polo-box domain in complex with PL-74
分子名称: GLYCEROL, PL-74, SULFATE ION, ...
著者Lee, W.C, Song, J.H, Kim, H.Y.
登録日2013-07-08
公開日2013-12-11
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Exploring the binding nature of pyrrolidine pocket-dependent interactions in the polo-box domain of polo-like kinase 1
Plos One, 8, 2013
4LKU
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BU of 4lku by Molmil
Structure of the C-terminal domain of the E. coli mechanosensitive channel of large conductance
分子名称: Large-conductance mechanosensitive channel
著者Walton, T.A, Rees, D.C.
登録日2013-07-08
公開日2013-10-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure and stability of the C-terminal helical bundle of the E. coli mechanosensitive channel of large conductance.
Protein Sci., 22, 2013
4WPZ
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BU of 4wpz by Molmil
Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis
分子名称: Cytochrome P450, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE
著者Kang, L.W, Kim, D.H, Pham, T.V, Han, S.H.
登録日2014-10-21
公開日2015-04-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A.
Arch.Biochem.Biophys., 575, 2015
4LH3
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BU of 4lh3 by Molmil
Structure of mouse 1-Pyrroline-5-Carboxylate Dehydrogenase (ALDH4A1) complexed with glutarate
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, GLUTARIC ACID, ...
著者Pemberton, T.A, Tanner, J.J.
登録日2013-06-30
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.813 Å)
主引用文献Structural basis of substrate selectivity of Delta (1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): Semialdehyde chain length.
Arch.Biochem.Biophys., 538, 2013
4LKV
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BU of 4lkv by Molmil
Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK
分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Emptage, R.P, Tonthat, N.K, York, J.D, Schumacher, M.A, Zhou, P.
登録日2013-07-08
公開日2014-07-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5109 Å)
主引用文献Structural Basis of Lipid Binding for the Membrane-embedded Tetraacyldisaccharide-1-phosphate 4'-Kinase LpxK.
J.Biol.Chem., 289, 2014
4LMI
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BU of 4lmi by Molmil
Crystal structure of putative ketosteroid isomerase from Kribbella flavida DSM 17836
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Uncharacterized protein
著者Chang, C, Chhor, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2013-07-10
公開日2013-07-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of putative ketosteroid isomerase from Kribbella flavida DSM 17836
To be Published
4LH1
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BU of 4lh1 by Molmil
Structure of mouse 1-Pyrroline-5-Carboxylate Dehydrogenase (ALDH4A1) complexed with malonate
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, MALONIC ACID, ...
著者Pemberton, T.A, Tanner, J.J.
登録日2013-06-30
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.673 Å)
主引用文献Structural basis of substrate selectivity of Delta (1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): Semialdehyde chain length.
Arch.Biochem.Biophys., 538, 2013
4LJQ
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Crystal structure of the catalytic core of E3 ligase HOIP
分子名称: E3 ubiquitin-protein ligase RNF31, ZINC ION
著者Stieglitz, B, Rana, R.R, Koliopoulos, M.G, Morris-Davies, A.C, Christodoulou, E, Howell, S, Brown, N.R, Rittinger, K.
登録日2013-07-05
公開日2013-10-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503, 2013
4LEH
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BU of 4leh by Molmil
Crystal structure of a bile-acid 7-alpha dehydratase (CLOSCI_03134) from Clostridium scindens ATCC 35704 at 2.90 A resolution
分子名称: Bile acid 7-alpha dehydratase, BaiE, SULFATE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2013-06-25
公開日2013-08-21
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a bile-acid 7-alpha dehydratase (CLOSCI_03134) from Clostridium scindens ATCC 35704 at 2.90 A resolution
To be published
4LGU
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BU of 4lgu by Molmil
Crystal structure of clAP1 BIR3 bound to T3226692
分子名称: (3S,8aR)-N-((R)-chroman-4-yl)-2-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)octahydropyrrolo[1,2-a]pyrazine-3-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION
著者Dougan, D.R, Mol, C.D, Snell, G.P.
登録日2013-06-28
公開日2013-08-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design, stereoselective synthesis, and biological evaluation of novel tri-cyclic compounds as inhibitor of apoptosis proteins (IAP) antagonists.
Bioorg.Med.Chem., 21, 2013
4LKL
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BU of 4lkl by Molmil
Crystal structure of Plk1 Polo-box domain in complex with PL-55
分子名称: ADAMANTANE, PL-55, Serine/threonine-protein kinase PLK1
著者Lee, W.C, Song, J.H, Kim, H.Y.
登録日2013-07-08
公開日2013-12-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Exploring the binding nature of pyrrolidine pocket-dependent interactions in the polo-box domain of polo-like kinase 1
Plos One, 8, 2013
4LKR
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BU of 4lkr by Molmil
Crystal structure of deoD-3 gene product from Shewanella oneidensis MR-1, NYSGRC target 029437
分子名称: Purine nucleoside phosphorylase DeoD-type
著者Malashkevich, V.N, Bonanno, J.B, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-07-08
公開日2013-07-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of deoD-3 gene product from Shewanella oneidensis MR-1, NYSGRC target 029437
To be Published
4LK0
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BU of 4lk0 by Molmil
Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex
分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.9103 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LOA
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BU of 4loa by Molmil
X-ray structure of the de-novo design amidase at the resolution 1.8A, Northeast Structural Genomics Consortium (NESG) Target OR398
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, De-novo design amidase
著者Kuzin, A, Lew, S, Vorobiev, S.M, Seetharaman, J, Sahdev, S, Xiao, R, Maglaqui, M, Kogan, S, Khersonsky, O, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2013-07-12
公開日2013-08-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.819 Å)
主引用文献Northeast Structural Genomics Consortium Target OR398
To be Published
4WEG
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BU of 4weg by Molmil
influenza virus neuraminidase N9 in complex 2,3-difluorosialic acid
分子名称: (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid, (3R,4R,5R,6R)-5-(acetylamino)-3-fluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4,5,6-tetrahydropyranium-2-carboxylate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Streltsov, V.A, Pilling, P, Barrett, S, McKimm-Breschkin, J.
登録日2014-09-10
公開日2015-09-16
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalytic mechanism and novel receptor binding sites of human parainfluenza virus type 3 hemagglutinin-neuraminidase (hPIV3 HN)
Antiviral Res., 123, 2015

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