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7LS4
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Co-complex CYP46A1 with 9129 (1b)
分子名称: Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, [5,5-dimethyl-3-(2-methylphenyl)-4~{H}-pyrazol-1-yl]-pyridin-4-yl-methanone
著者Lane, W, Yano, J.
登録日2021-02-17
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H).
J.Med.Chem., 64, 2021
4V8E
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Crystal structure analysis of ribosomal decoding (near-cognate tRNA-tyr complex).
分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2011-12-07
公開日2014-07-09
最終更新日2019-07-03
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
9MHT
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CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
分子名称: 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
著者O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X.
登録日1998-08-07
公開日1998-12-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
4V8D
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Structure analysis of ribosomal decoding (cognate tRNA-tyr complex).
分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2011-12-07
公開日2014-07-09
最終更新日2019-07-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4F9G
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Crystal structure of STING complex with Cyclic di-GMP.
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Transmembrane protein 173
著者Kabaleeswaran, V, Wu, H.
登録日2012-05-18
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING.
Mol.Cell, 46, 2012
4V5F
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The structure of the ribosome with elongation factor G trapped in the post-translocational state
分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Gao, Y.-G, Selmer, M, Dunham, C.M, Weixlbaumer, A, Kelley, A.C, Ramakrishnan, V.
登録日2009-09-01
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The structure of the ribosome with elongation factor G trapped in the posttranslocational state.
Science, 326, 2009
6ZL7
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CRYSTAL STRUCTURE OF C173S MUTATION IN THE PMGL2 ESTERASE FROM PERMAFROST METAGENOMIC LIBRARY
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, MAGNESIUM ION, PMGL2
著者Goryaynova, D.A, Boyko, K.M, Nikolaeva, A.Y, Korzhenevskiy, D.A, Kryukova, M.V, Petrovskaya, L.E, Novototskaya-Vlasova, K.A, Rivkina, E.M, Dolgikh, D.A, Kirpichnikov, M.P, Popov, V.O.
登録日2020-06-30
公開日2020-07-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献CRYSTAL STRUCTURE OF C173S MUTATION IN THE PMGL2 ESTERASE FROM PERMAFROST METAGENOMIC LIBRARY
To Be Published
4V95
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Crystal structure of YAEJ bound to the 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A.
登録日2012-01-27
公開日2014-07-09
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome.
Science, 335, 2012
1VRM
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BU of 1vrm by Molmil
Crystal structure of the apbe protein (tm1553) from thermotoga maritima msb8 at 1.58 A resolution
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, UNKNOWN LIGAND, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2005-03-10
公開日2005-03-22
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution.
Proteins, 64, 2006
8SJ1
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Structure of ternary complex of cGAS with dsDNA and bound 3'-dATP
分子名称: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ...
著者Wu, S, Sohn, J.
登録日2023-04-17
公開日2024-04-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
8SJ0
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Structure of ternary complex of cGAS with dsDNA and bound 2'-dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ...
著者Wu, S, Sohn, J.
登録日2023-04-17
公開日2024-04-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
6ZHJ
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3D electron diffraction structure of thermolysin from Bacillus thermoproteolyticus
分子名称: CALCIUM ION, Thermolysin, ZINC ION
著者Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P.
登録日2020-06-23
公開日2021-01-27
最終更新日2024-01-24
実験手法ELECTRON CRYSTALLOGRAPHY (3.26 Å)
主引用文献Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
6ZHN
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3D electron diffraction structure of thaumatin from Thaumatococcus daniellii
分子名称: CHLORIDE ION, Thaumatin-1
著者Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P.
登録日2020-06-23
公開日2021-01-27
最終更新日2024-01-24
実験手法ELECTRON CRYSTALLOGRAPHY (2.76 Å)
主引用文献Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
8SKT
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Structure of ternary complex of mouse cGAS with dsDNA and bound ATP with 5 mM Mn2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
著者Wu, S, Sohn, J.
登録日2023-04-20
公開日2024-04-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
6ZK8
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Native crystal structure of anaerobic F420H2-Oxidase from Methanothermococcus thermolithotrophicus at 1.8A resolution
分子名称: Coenzyme F420H2 oxidase (FprA), DI(HYDROXYETHYL)ETHER, FE (III) ION, ...
著者Engilberge, S, Wagner, T, Carpentier, P, Girard, E, Shima, S.
登録日2020-06-30
公開日2020-11-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Krypton-derivatization highlights O 2 -channeling in a four-electron reducing oxidase.
Chem.Commun.(Camb.), 56, 2020
5VGJ
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Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90, bound to a scaffolded WITO V1V2 domain
分子名称: 1FD6-V1V2-WITO, 2-acetamido-2-deoxy-beta-D-glucopyranose, VRC38.01 Fab Heavy Chain, ...
著者Gorman, J, Li, J, Kwong, P.D.
登録日2017-04-11
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.456 Å)
主引用文献Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Immunity, 46, 2017
8SHY
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BU of 8shy by Molmil
Structure of binary complex of mouse cGAS QN and bound ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ZINC ION
著者Wu, S, Sohn, J.
登録日2023-04-14
公開日2024-04-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
6ZA7
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Structure of the apo transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ...
著者Morera, S, Vigouroux, A, Legrand, P.
登録日2020-06-04
公開日2020-12-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
1W8U
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CBM29-2 mutant D83A complexed with mannohexaose: Probing the Mechanism of Ligand Recognition by Family 29 Carbohydrate Binding Modules
分子名称: NON CATALYTIC PROTEIN 1, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose
著者Flint, J, Bolam, D.N, Nurizzo, D, Taylor, E.J, Williamson, M.P, Walters, C, Davies, G.J, Gilbert, H.J.
登録日2004-09-28
公開日2005-03-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
4WBD
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The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, BSHC, CITRIC ACID, ...
著者Cook, P.D, VanDuinen, A.J, Winchell, K.R.
登録日2014-09-03
公開日2014-12-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献X-ray Crystallographic Structure of BshC, a Unique Enzyme Involved in Bacillithiol Biosynthesis.
Biochemistry, 54, 2015
6ZDY
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Crystal structure of WT murine S100A9 bound to calcium and zinc
分子名称: CALCIUM ION, Protein S100-A9, SULFATE ION, ...
著者Yatime, L.
登録日2020-06-15
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Divalent cations influence the dimerization mode of murine S100A9 protein by modulating its disulfide bond pattern.
J.Struct.Biol., 213, 2020
4F9E
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Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
分子名称: Transmembrane protein 173
著者Kabaleeswaran, V, Wu, H.
登録日2012-05-18
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING.
Mol.Cell, 46, 2012
8SJ2
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Structure of ternary complex of cGAS with dsDNA and bound ATP and 2'-dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ...
著者Wu, S, Sohn, J.
登録日2023-04-17
公開日2024-04-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
4V8B
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Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex).
分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2011-12-06
公開日2014-07-09
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
1W9X
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Bacillus halmapalus alpha amylase
分子名称: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ALPHA AMYLASE, CALCIUM ION, ...
著者Davies, G.J, Brzozowski, A.M, Dauter, Z, Rasmussen, M.D, Borchert, T.V, Wilson, K.S.
登録日2004-10-20
公開日2005-02-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of a Bacillus Halmapalus Family 13 Alpha-Amylase, Bha, in Complex with an Acarbose-Derived Nonasaccharide at 2.1 A Resolution
Acta Crystallogr.,Sect.D, 61, 2005

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