4LKV

Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK

Summary for 4LKV

Entry DOI	10.2210/pdb4lkv/pdb
Related	4ehw 4ehx 4ehy 4itl 4itm 4itn
Descriptor	Tetraacyldisaccharide 4'-kinase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	p-loop containing nucleotide triphosphate hydrolase, kinase, membrane protein, transferase
Biological source	Aquifex aeolicus
Total number of polymer chains	4
Total formula weight	149476.67
Authors	Emptage, R.P.,Tonthat, N.K.,York, J.D.,Schumacher, M.A.,Zhou, P. (deposition date: 2013-07-08, release date: 2014-07-09, Last modification date: 2024-02-28)
Primary citation	Emptage, R.P.,Tonthat, N.K.,York, J.D.,Schumacher, M.A.,Zhou, P. Structural Basis of Lipid Binding for the Membrane-embedded Tetraacyldisaccharide-1-phosphate 4'-Kinase LpxK. J.Biol.Chem., 289:24059-24068, 2014 Cited by PubMed: 25023290 DOI: 10.1074/jbc.M114.589986 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5109 Å)

Structure validation