4EHW

Crystal structure of LpxK from Aquifex aeolicus at 2.3 angstrom resolution

Summary for 4EHW

• Entry DOI: 10.2210/pdb4ehw/pdb
• Related: 4EHX 4EHY
• Descriptor: Tetraacyldisaccharide 4'-kinase, GLYCEROL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: membrane protein, kinase, lipid a, p-loop, p-loop containing nucleoside triphosphate hydrolase, disaccharide-1-phosphate 4'-kinase, membrane, transferase, lipid metabolism, tetraacyldisaccharide 4'-kinase
• Biological source: Aquifex aeolicus
• Total number of polymer chains: 1
• Total formula weight: 37848.22

Authors

Emptage, R.P.,Daughtry, K.D.,Pemble IV, C.W.,Raetz, C.R.H. (deposition date: 2012-04-04, release date: 2012-08-29, Last modification date: 2024-02-28)

• Primary citation: Emptage, R.P.,Daughtry, K.D.,Pemble, C.W.,Raetz, C.R.; Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface.; Proc.Natl.Acad.Sci.USA, 109:12956-12961, 2012; PubMed: 22826246; DOI: 10.1073/pnas.1206072109

Experimental method

X-RAY DIFFRACTION (2.3 Å)