4EHW

Crystal structure of LpxK from Aquifex aeolicus at 2.3 angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0009029	molecular_function	lipid-A 4'-kinase activity
A	0009244	biological_process	lipopolysaccharide core region biosynthetic process
A	0009245	biological_process	lipid A biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 400

Chain	Residue
A	GLU189
A	ARG206

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 401

Chain	Residue
A	LYS30
A	ASP266
A	PHE267
A	THR268
A	HOH550
A	HOH551

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MPD A 402

Chain	Residue
A	LYS156
A	LYS158
A	TYR187
A	GLU191
A	GLY48

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MPD A 403

Chain	Residue
A	THR278
A	PRO279
A	HOH507

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 404

Chain	Residue
A	ASN295

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MPD A 405

Chain	Residue
A	ARG178
A	PHE216

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MPD A 408

Chain	Residue
A	LYS26
A	PHE28

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site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 409

Chain	Residue
A	GLY27
A	PHE28
A	SER265
A	ASP266
A	PHE267
A	THR268

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00409","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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