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4EHY

Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution

Summary for 4EHY
Entry DOI10.2210/pdb4ehy/pdb
Related4EHW 4EHX
DescriptorTetraacyldisaccharide 4'-kinase, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... (6 entities in total)
Functional Keywordsmembrane protein, kinase, lipid a, p-loop, p-loop containing nucleoside triphosphate hydrolase, disaccharide-1-phosphate 4'-kinase, membrane, transferase, lipid metabolism, tetraacyldisaccharide 4'-kinase
Biological sourceAquifex aeolicus
Total number of polymer chains1
Total formula weight37360.97
Authors
Emptage, R.P.,Daughtry, K.D.,Pemble IV, C.W.,Raetz, C.R.H. (deposition date: 2012-04-04, release date: 2012-08-29, Last modification date: 2023-09-13)
Primary citationEmptage, R.P.,Daughtry, K.D.,Pemble, C.W.,Raetz, C.R.
Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface.
Proc.Natl.Acad.Sci.USA, 109:12956-12961, 2012
Cited by
PubMed: 22826246
DOI: 10.1073/pnas.1206072109
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.199 Å)
Structure validation

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