4LKV
Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009029 | molecular_function | lipid-A 4'-kinase activity |
| A | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0009029 | molecular_function | lipid-A 4'-kinase activity |
| B | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| B | 0009245 | biological_process | lipid A biosynthetic process |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009029 | molecular_function | lipid-A 4'-kinase activity |
| C | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| C | 0009245 | biological_process | lipid A biosynthetic process |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0009029 | molecular_function | lipid-A 4'-kinase activity |
| D | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| D | 0009245 | biological_process | lipid A biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EPE A 401 |
| Chain | Residue |
| A | LYS145 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE LP4 A 402 |
| Chain | Residue |
| A | TYR13 |
| A | ARG72 |
| A | ARG171 |
| A | LP5403 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE LP5 A 403 |
| Chain | Residue |
| A | LP4402 |
| A | ARG72 |
| A | GLU117 |
| A | ARG119 |
| A | HIS143 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE LP4 C 401 |
| Chain | Residue |
| C | VAL46 |
| C | ARG72 |
| C | ARG171 |
| C | LP5402 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE LP5 C 402 |
| Chain | Residue |
| C | ARG72 |
| C | GLU117 |
| C | ARG119 |
| C | GLN142 |
| C | HIS143 |
| C | ARG171 |
| C | LP4401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00409","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
