Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex

Summary for 4LK0

DescriptorDNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywordsdna directed rna polymerase, transferase
Biological sourceEscherichia coli
Cellular locationCytoplasm (Potential) P00579
Total number of polymer chains14
Total molecular weight874013.63
Bae, B.,Darst, S.A. (deposition date: 2013-07-05, release date: 2013-11-13, Last modification date: 2013-12-18)
Primary citation
Bae, B.,Davis, E.,Brown, D.,Campbell, E.A.,Wigneshweraraj, S.,Darst, S.A.
Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110:19772-19777, 2013
PubMed: 24218560 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1314576110
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26112 0.3% 8.1% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-18