6FLS
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1F8T
| FAB (LNKB-2) OF MONOCLONAL ANTIBODY, CRYSTAL STRUCTURE | 分子名称: | ANTIBODY FAB FRAGMENT (HEAVY CHAIN), ANTIBODY FAB FRAGMENT (LIGHT CHAIN) | 著者 | Fokin, A.V, Afonin, P.V, Mikhailova, I.I, Tsygannik, I.N, Mareeva, T.I. | 登録日 | 2000-07-05 | 公開日 | 2001-07-05 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Spatial structure of a Fab-fragment of a monoclonal antibody to human interleukin-2 in two crystalline forms at a resolution of 2.2 and 2.9 angstroms Bioorg.Khim., 26, 2000
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8TL1
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5LZZ
| Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2016-10-02 | 公開日 | 2016-11-30 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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8TKA
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6FPK
| Co-translational folding intermediate dictates membrane targeting of the signal recognition particle (SRP)- receptor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Signal recognition particle receptor FtsY | 著者 | Karniel, A, Mrusek, D, Steinchen, W, Dym, O, Bange, G, Bibi, E. | 登録日 | 2018-02-11 | 公開日 | 2018-05-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Co-translational Folding Intermediate Dictates Membrane Targeting of the Signal Recognition Particle Receptor. J. Mol. Biol., 430, 2018
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8TW1
| Crystal structure of Lys2972, a phage endolysin targeting Streptococcus thermophilus | 分子名称: | Endolysin Lys2972, GLYCEROL, SODIUM ION | 著者 | Zhu, X, Moineau, S, Shi, R. | 登録日 | 2023-08-18 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | Fermentation Practices Select for Thermostable Endolysins in Phages. Mol.Biol.Evol., 41, 2024
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5LF3
| Human 20S proteasome complex with Bortezomib at 2.1 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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1FFN
| CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33(C9M) | 分子名称: | BETA-2 MICROGLOBULIN, BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A. | 登録日 | 2000-07-25 | 公開日 | 2002-12-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Peptidic termini play a significant role in TCR recognition J.IMMUNOL., 169, 2002
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6FNU
| Structure of S. cerevisiae Methylenetetrahydrofolate reductase 1, catalytic domain | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Methylenetetrahydrofolate reductase 1 | 著者 | Kopec, J, Rembeza, E, Bezerra, G.A, Newman, J, Bountra, C, Froese, D.S, Baumgartner, M, Yue, W.W, Structural Genomics Consortium (SGC) | 登録日 | 2018-02-05 | 公開日 | 2018-03-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition. Nat Commun, 9, 2018
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5LF1
| Human 20S proteasome complex with Dihydroeponemycin at 2.0 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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7TNG
| Kringle domain of human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) | 分子名称: | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | 著者 | Guarino, S.R, Di Bello, A, Palamini, M, Forneris, F. | 登録日 | 2022-01-21 | 公開日 | 2022-05-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1) Acta Crystallogr.,Sect.F, 78, 2022
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6FPJ
| Structure of the AMPAR GluA3 N-terminal domain bound to phosphate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Herguedas, B, Garcia-Nafria, J, Greger, I. | 登録日 | 2018-02-09 | 公開日 | 2018-12-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain. Structure, 27, 2019
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8TQV
| Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor X20403 | 分子名称: | 4-(2-{(4M)-4-[(6M)-6-(2,5-dimethoxyphenyl)pyridin-3-yl]-1H-1,2,3-triazol-1-yl}ethyl)-N-{[1-(methoxymethyl)cyclopropyl]methyl}-N-methylbenzamide, Polyketide synthase Pks13, SULFATE ION | 著者 | Krieger, I.V, Sacchettini, J.C. | 登録日 | 2023-08-08 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening. Acs Infect Dis., 10, 2024
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1FJW
| THERMOLYSIN (50 MM PHENOL SOAKED) | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, PHENOL, ... | 著者 | English, A.C, Groom, C.R, Hubbard, R.E. | 登録日 | 2000-08-08 | 公開日 | 2001-04-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Experimental and computational mapping of the binding surface of a crystalline protein. Protein Eng., 14, 2001
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6IFS
| KsgA from Bacillus subtilis 168 | 分子名称: | Ribosomal RNA small subunit methyltransferase A | 著者 | Bhujbalrao, R, Anand, R. | 登録日 | 2018-09-21 | 公開日 | 2019-01-30 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Deciphering Determinants in Ribosomal Methyltransferases That Confer Antimicrobial Resistance. J. Am. Chem. Soc., 141, 2019
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7TI0
| Structure of CTX-M-15 bound to RPX-7063 at 1.5A | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ... | 著者 | Clifton, M.C, Abendroth, J, Hecker, S.J, Edwards, T.E. | 登録日 | 2022-01-12 | 公開日 | 2022-05-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Broad-spectrum cyclic boronate beta-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability. Bioorg.Med.Chem., 62, 2022
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5LJL
| Streptococcus pneumonia TIGR4 flavodoxin: structural and biophysical characterization of a novel drug target | 分子名称: | Flavodoxin, PHOSPHATE ION | 著者 | Rodriguez-Cardenas, A, Rojas, A.L, Velazquez-Campoy, A, Hurtado-Guerrero, R, Sancho, J. | 登録日 | 2016-07-18 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Streptococcus pneumoniae TIGR4 Flavodoxin: Structural and Biophysical Characterization of a Novel Drug Target. Plos One, 11, 2016
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6FLN
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6FWJ
| Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-Glc-1,3-(1,2-anhydro-carba-mannosamine) and alpha-1,2-mannobiose | 分子名称: | (1~{R},2~{R},3~{R},4~{R},6~{R})-4-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3-diol, ACETATE ION, Glycosyl hydrolase family 71, ... | 著者 | Sobala, L.F, Speciale, G, Hakki, Z, Fernandes, P.Z, Raich, L, Rojas-Cervellera, V, Bennet, A, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Lu, D, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J. | 登録日 | 2018-03-06 | 公開日 | 2019-09-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | An Epoxide Intermediate in Glycosidase Catalysis. Acs Cent.Sci., 6, 2020
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6IV8
| the selenomethionine(SeMet)-derived Cas13d binary complex | 分子名称: | MAGNESIUM ION, RNA (51-MER), RNA (53-MER), ... | 著者 | Zhang, B, Ye, Y.M, Ye, W.W, OuYang, S.Y. | 登録日 | 2018-12-02 | 公開日 | 2019-06-19 | 最終更新日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d. Nat Commun, 10, 2019
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6FN9
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5LKZ
| Crystal structure of the p300 acetyltransferase catalytic core with crotonyl-coenzyme A. | 分子名称: | CROTONYL COENZYME A, GLYCEROL, Histone acetyltransferase p300,Histone acetyltransferase p300, ... | 著者 | Kaczmarska, Z, Ortega, E, Marquez, J.A, Panne, D. | 登録日 | 2016-07-25 | 公開日 | 2016-11-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of p300 in complex with acyl-CoA variants. Nat. Chem. Biol., 13, 2017
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4RIU
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5LXV
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