Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 23 results
4QLI
DownloadVisualize
BU of 4qli by Molmil
A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
Descriptor: 14-3-3 protein sigma, GLYCEROL, MAGNESIUM ION, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2014-06-12
Release date:2015-06-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
To be Published
5JM4
DownloadVisualize
BU of 5jm4 by Molmil
Crystal structure of 14-3-3zeta in complex with a cyclic peptide involving an adamantyl and a dicarboxy side chain
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, GLN-GLY-MKD-ANG-ASP-MKD-LEU-ASP-LEU-ALA-CLU
Authors:Bier, D, Krueger, D, Glas, A, Wallraven, K, Ottmann, C, Hennig, S, Grossmann, T.
Deposit date:2016-04-28
Release date:2017-05-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein-Protein Interactions.
J. Med. Chem., 60, 2017
5OEG
DownloadVisualize
BU of 5oeg by Molmil
Molecular tweezers modulate 14-3-3 protein-protein interactions
Descriptor: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION
Authors:Bier, D, Ottmann, C.
Deposit date:2017-07-07
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Molecular tweezers modulate 14-3-3 protein-protein interactions.
Nat Chem, 5, 2013
5OEH
DownloadVisualize
BU of 5oeh by Molmil
Molecular tweezers modulate 14-3-3 protein-protein interactions.
Descriptor: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2017-07-07
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular tweezers modulate 14-3-3 protein-protein interactions.
Nat Chem, 5, 2013
5M37
DownloadVisualize
BU of 5m37 by Molmil
The molecular tweezer CLR01 stabilizes a disordered protein-protein interface
Descriptor: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein zeta/delta, BENZOIC ACID, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2016-10-14
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
J. Am. Chem. Soc., 139, 2017
5M36
DownloadVisualize
BU of 5m36 by Molmil
The molecular tweezer CLR01 stabilizes a disordered protein-protein interface
Descriptor: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein zeta/delta, BENZOIC ACID, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2016-10-14
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
J. Am. Chem. Soc., 139, 2017
4JDD
DownloadVisualize
BU of 4jdd by Molmil
14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN
Authors:Bier, D, Ottmann, C.
Deposit date:2013-02-25
Release date:2013-05-15
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4JC3
DownloadVisualize
BU of 4jc3 by Molmil
14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, MAGNESIUM ION
Authors:Bier, D, Ottmann, C.
Deposit date:2013-02-21
Release date:2013-05-15
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
5M35
DownloadVisualize
BU of 5m35 by Molmil
The molecular tweezer CLR01 stabilizes a disordered protein-protein interface
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2016-10-14
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
J. Am. Chem. Soc., 139, 2017
4N7Y
DownloadVisualize
BU of 4n7y by Molmil
Crystal structure of 14-3-3zeta in complex with a 8-carbon-linker cyclic peptide derived from ExoS
Descriptor: 14-3-3 protein zeta/delta, Exoenzyme S
Authors:Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C.
Deposit date:2013-10-16
Release date:2014-02-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction.
Angew.Chem.Int.Ed.Engl., 53, 2014
4N84
DownloadVisualize
BU of 4n84 by Molmil
Crystal structure of 14-3-3zeta in complex with a 12-carbon-linker cyclic peptide derived from ExoS
Descriptor: 14-3-3 protein zeta/delta, Exoenzyme S
Authors:Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C.
Deposit date:2013-10-17
Release date:2014-02-19
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction.
Angew.Chem.Int.Ed.Engl., 53, 2014
4N7G
DownloadVisualize
BU of 4n7g by Molmil
Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS
Descriptor: 14-3-3 protein zeta/delta, Exoenzyme S, HEXAETHYLENE GLYCOL
Authors:Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C.
Deposit date:2013-10-15
Release date:2014-02-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction.
Angew.Chem.Int.Ed.Engl., 53, 2014
6FNC
DownloadVisualize
BU of 6fnc by Molmil
Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ...
Authors:Bier, D, Ottann, C.
Deposit date:2018-02-02
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
6FN9
DownloadVisualize
BU of 6fn9 by Molmil
Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2018-02-02
Release date:2018-07-04
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
6FNB
DownloadVisualize
BU of 6fnb by Molmil
Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2018-02-02
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
6FNA
DownloadVisualize
BU of 6fna by Molmil
Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2018-02-02
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
5EXA
DownloadVisualize
BU of 5exa by Molmil
Small-molecule stabilization of the 14-3-3/Gab2 PPI interface
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, Fusicoccin A-THF derivative, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2015-11-23
Release date:2016-05-04
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.
Chemmedchem, 11, 2016
5EWZ
DownloadVisualize
BU of 5ewz by Molmil
Small-molecule stabilization of the 14-3-3/Gab2 PPI interface
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, GRB2-associated-binding protein 2
Authors:Bier, D, Ottmann, C.
Deposit date:2015-11-23
Release date:2016-05-04
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.
Chemmedchem, 11, 2016
5J31
DownloadVisualize
BU of 5j31 by Molmil
Crystal structure of 14-3-3zeta in complex with an alkyne cross-linked cyclic peptide derived from ExoS
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, Exoenzyme S
Authors:Wallraven, K, Cromm, P, Bier, D, Glas, A, Grossmann, T.
Deposit date:2016-03-30
Release date:2016-10-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Constraining an Irregular Peptide Secondary Structure through Ring-Closing Alkyne Metathesis.
Chembiochem, 17, 2016
5BUG
DownloadVisualize
BU of 5bug by Molmil
Crystal structure of human phosphatase PTEN oxidized by H2O2
Descriptor: L(+)-TARTARIC ACID, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Authors:Lee, C.-U, Bier, D, Hennig, S, Grossmann, T.N.
Deposit date:2015-06-03
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes.
Angew.Chem.Int.Ed.Engl., 54, 2015
5BZX
DownloadVisualize
BU of 5bzx by Molmil
Crystal structure of human phosphatase PTEN treated with a bisperoxovanadium complex
Descriptor: L(+)-TARTARIC ACID, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, VANADATE ION
Authors:Lee, C.-U, Bier, D, Hennig, S, Grossmann, T.N.
Deposit date:2015-06-11
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes.
Angew.Chem.Int.Ed.Engl., 54, 2015
5BZZ
DownloadVisualize
BU of 5bzz by Molmil
Crystal structure of human phosphatase PTEN in its reduced state
Descriptor: L(+)-TARTARIC ACID, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Authors:Lee, C.-U, Bier, D, Hennig, S, Grossmann, T.N.
Deposit date:2015-06-11
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y32
DownloadVisualize
BU of 4y32 by Molmil
Crystal structure of C-terminal modified Tau peptide-hybrid 109B with 14-3-3sigma
Descriptor: (2S)-2-(2-methoxyethyl)pyrrolidine, 14-3-3 protein sigma, ARG-THR-PRO-SEP-LEU-PRO-CNC(C(C)O)C(=O)N1CCCC1CCOC
Authors:Bartel, M, Milroy, L, Bier, D, Brunsveld, L, Ottmann, C.
Deposit date:2015-02-10
Release date:2015-12-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Stabilizer-Guided Inhibition of Protein-Protein Interactions.
Angew.Chem.Int.Ed.Engl., 54, 2015

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon