5EWZ
Small-molecule stabilization of the 14-3-3/Gab2 PPI interface
Summary for 5EWZ
Entry DOI | 10.2210/pdb5ewz/pdb |
Related | 4FJ3 4IHL 4N7G |
Descriptor | 14-3-3 protein zeta/delta, GRB2-associated-binding protein 2, BENZOIC ACID, ... (5 entities in total) |
Functional Keywords | 14-3-3, gab2, protein, diphosphorylation, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 54749.69 |
Authors | Bier, D.,Ottmann, C. (deposition date: 2015-11-23, release date: 2016-05-04, Last modification date: 2018-12-19) |
Primary citation | Bier, D.,Bartel, M.,Sies, K.,Halbach, S.,Higuchi, Y.,Haranosono, Y.,Brummer, T.,Kato, N.,Ottmann, C. Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface. Chemmedchem, 11:911-918, 2016 Cited by PubMed: 26644359DOI: 10.1002/cmdc.201500484 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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