4FJ3

14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide

Summary for 4FJ3

• Entry DOI: 10.2210/pdb4fj3/pdb
• Related: 1A4O 3IQJ 3NKX
• Descriptor: 14-3-3 protein zeta/delta, RAF proto-oncogene serine/threonine-protein kinase (3 entities in total)
• Functional Keywords: 14-3-3 fold, all alpha-helical, adapter protein, protein binding-transferase complex, protein binding/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P63104 P04049
• Total number of polymer chains: 3
• Total formula weight: 57624.64

Authors

Ottmann, C.,Molzan, M. (deposition date: 2012-06-11, release date: 2012-09-05, Last modification date: 2013-07-10)

• Primary citation: Molzan, M.,Ottmann, C.; Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3zeta dimer; J.Mol.Biol., 423:486-495, 2012; PubMed: 22922483; DOI: 10.1016/j.jmb.2012.08.009

Experimental method

X-RAY DIFFRACTION (1.95 Å)